intrinsic and extrinsic control of stroke volume Flashcards
Stroke volume usually referring to right or left ventricle?
left ventricle because its the one that pushes blood into aortic arch
isovolumetric contraction: heart contracts but two valves are closed, no volume change as a result. contraction causes pressure spike or decrease?
spike
Isovolumetric relaxation: no change in volume, relaxation causes pressure to spike or drop?
drop
stroke volume = endiastolic volume - end systolic volume. refers to ??? volume
ventricular volume
stroke volume depends on preload: amount of muscle stretch immediately prior to ???
contraction
Frank-Starlin Law (preload and SV) stretching myocytes before activation leads to a more powerful force generation and therefore greater ???
stroke volume
TRUE or FALSE: length-tension and FS law: 75% of sarcomere length shortened/overlapped, tension is greatly reduced
True
TRUE or FALSE: Length-tension and FS law: 100% of sarcomere length at resting length = optimal sarcomere operating length = greater ability for sliding filament mechanism to occur
TRUE
TRUE or FALSE: Stroke Volume depends on afterload (MAP/downstream blood pressure= BP in aorta that the contraction is fighting against to open up semi-lunar valve)
TRUE
downstream BP that impedes cardiac emptying: delays aortic valve opening because valve cannot open until ventricular pressure is less or more than aortic pressure?
more
does the aortic pressure easily become higher than ventricular pressure? if so, would valves close rapidly or slowly in response?
YES, valves rapidly close
Stroke volume and contractility: increase in contractility = increase time heart contracts (i.e it contracts for longer) = more blood ejected out. Caused by increased ??? levels in blood
Ca2+ levels in blood
Stroke volume also depends on Heart rate: increased heart rate = increased stroke volume (up to a certain point) and cardiac output due to ??? entry into blood
increased Ca2+ entry
(Extrinsic) SNS innervation of contractile cells: noradrenaline activation = increased or decreased contractility? this causes increased SV
increased contractility
(Extrinsic) PNSS innervation of contractile cells: acetylcholine. occurs mainly in ??? node = HR bradycardia. Contractile cells = minimal PNS innervation of cardiac muscle = minor decrease in contractility
SA node