intrinsic and extrinsic control of stroke volume Flashcards

1
Q

Stroke volume usually referring to right or left ventricle?

A

left ventricle because its the one that pushes blood into aortic arch

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2
Q

isovolumetric contraction: heart contracts but two valves are closed, no volume change as a result. contraction causes pressure spike or decrease?

A

spike

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3
Q

Isovolumetric relaxation: no change in volume, relaxation causes pressure to spike or drop?

A

drop

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4
Q

stroke volume = endiastolic volume - end systolic volume. refers to ??? volume

A

ventricular volume

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5
Q

stroke volume depends on preload: amount of muscle stretch immediately prior to ???

A

contraction

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6
Q

Frank-Starlin Law (preload and SV) stretching myocytes before activation leads to a more powerful force generation and therefore greater ???

A

stroke volume

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7
Q

TRUE or FALSE: length-tension and FS law: 75% of sarcomere length shortened/overlapped, tension is greatly reduced

A

True

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8
Q

TRUE or FALSE: Length-tension and FS law: 100% of sarcomere length at resting length = optimal sarcomere operating length = greater ability for sliding filament mechanism to occur

A

TRUE

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9
Q

TRUE or FALSE: Stroke Volume depends on afterload (MAP/downstream blood pressure= BP in aorta that the contraction is fighting against to open up semi-lunar valve)

A

TRUE

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10
Q

downstream BP that impedes cardiac emptying: delays aortic valve opening because valve cannot open until ventricular pressure is less or more than aortic pressure?

A

more

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11
Q

does the aortic pressure easily become higher than ventricular pressure? if so, would valves close rapidly or slowly in response?

A

YES, valves rapidly close

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12
Q

Stroke volume and contractility: increase in contractility = increase time heart contracts (i.e it contracts for longer) = more blood ejected out. Caused by increased ??? levels in blood

A

Ca2+ levels in blood

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13
Q

Stroke volume also depends on Heart rate: increased heart rate = increased stroke volume (up to a certain point) and cardiac output due to ??? entry into blood

A

increased Ca2+ entry

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14
Q

(Extrinsic) SNS innervation of contractile cells: noradrenaline activation = increased or decreased contractility? this causes increased SV

A

increased contractility

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15
Q

(Extrinsic) PNSS innervation of contractile cells: acetylcholine. occurs mainly in ??? node = HR bradycardia. Contractile cells = minimal PNS innervation of cardiac muscle = minor decrease in contractility

A

SA node

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