into/cell pathology Flashcards

1
Q

what is prevalence

A

“proportion of cases”

how widespread the disease is

existing cases

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2
Q

what is incidence

A

“risk of contracting disease”

new cases

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3
Q

nociceptive pain is activated by what

A

nociceptive receptors

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4
Q

what are the ways to evaluate pain

A

visual analog scale

pain faces

numerical rating scale of 1-10

numerical rating scale
categorical pain scale
pain drawings
Mcgill

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5
Q

definition of addiction

A

dependence and a withdrawl cycle

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6
Q

what is the most common tx for bipolar

A

lithium

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7
Q

what is etiology

A

cause of disease

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8
Q

what are signs

A

when we describe things clinically, what we are describing

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9
Q

what is a symptom

A

what’s recorded subjectively by the patient

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10
Q

what is a nosocomial infection

A

infection you get from the hospital

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11
Q

what does idiopathic mean

A

unknown cause

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12
Q

where does pain travel through in the pain gate / neuromatrix theory of pain

A

pain travels through gates at the dorsal horn of the spinal cord

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13
Q

what hormones are released as response to stress in the body or brain

CENNA

A

cortisol
epinephrine
noradrenaline
norepinephrine
adrenaline

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14
Q

what is hyperalgesia

A

increased pain response (more pain than normal)

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15
Q

what helps w detoxification of drugs

A

smooth endoplasmic reticulum

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16
Q

what is hypoxia

A

reduced state of O2

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17
Q

what is it called when a cell decreases in size

A

atrophy

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18
Q

what is metaplasia

A

when a cell changes from one cell type to another

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19
Q

what is apoptosis

A

cells live our normal life span then die

programmed cell death

20
Q

what is liquefactive necrosis

A

when the brain liquefies

21
Q

how are anemias classified

A

RBC color
size
causative factor

22
Q

most common anemia that affects 20% of women

A

iron deficiency anemia

23
Q

anemia caused by lack of vitamin B12 and larger than normal RBC

A

pernicious anemia

24
Q

type of anemia that is genetically determined

A

sickle cell

25
clotting factor that's deficient in hemophilia type A
VIII - 8
26
what process is necrosis caused by
exogenous processes (outside of cell)
27
what is an intracellular accumulation
caused by overload of metabolites or inability to secrete excesses
28
what is hyperplasia
increase in number of cells that cause increase in size of tissue and organs
29
what is neoplasia
increase in growth of tissue - forms tumors
30
what is metaplasia
change of one mature cell type into another - change can be reversible
31
what is dysplasia
increase in numbers of cells and their rate of mitosis
32
what is anaplasia
where cells become less differentiated or devolve back into stem cells
33
what are some causes of cell injury
lack of O2 ischemia toxic injury microbial pathogens mediators of inflamm and immune reactions generic and metabolic disturbances
34
where does mitosis happen
nucleus - contains RNA, DNA
35
site of protein synthesis
ribosomes rough ER
36
what is anemia
reduction in quantity / quality of RBC impairs ability to carry O2 and leads to hypoxia in tissues
37
what is hemolytic anemia
RBC are destroyed faster than they are produced in bone marrow
38
what is epidemiology
incidence the distribution and control of disease
39
morbidity vs mortality
morbidity - how many ppl get it mortality - how many ppl will die from it
40
pain on skin in response to something that doesn't normally cause pain - hypersensitive --- whats the word for this
allodynia
41
what is hyperalgesia
increased pain response
42
what is paresthesia
painful feelings w no stimulus
43
pain gate theory
non painful input like massage closes the gates at the dorsal horns of the spinal cord to block painful input
44
hormones involved w stress
adrenaline noradrenaline cortisol
45
what is intractable pain
excruciating and constant, incurable
46
what disease is cancer of blood tissue/ bone marrow
leukemia