Internal Med Hematology Flashcards

1
Q

s/s of leukemia

A
  • fever
  • anemia
  • lymphadenopathy
  • bone pain
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

diagnosis of ALL

A
  • bone marrow biopsy
  • lymphoblasts
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

treatment of ALL

A
  • induction chemo and CNS prophylaxis
  • post-remission therapy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

diagnosis of CLL

A
  • lymphocytes
  • smudge cells
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

treatment of CLL

A

multidrug chemo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

diagnosis of AML

A
  • auer rods
  • myeloblasts
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

treatment of AML

A

multidrug chemo and postremission chemo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

diagnosis of CML

A
  • philadelphia chromosome
  • myelocytes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

treatment of CML

A

TK inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

S/S of Anemia of chronic disease

A

fatigue, weakness, DOE, anorexia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

treatment of anemia of chronic disease

A
  • treat underlying cause
  • EPO
  • transfusions
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

etiology of G6PD deficiency

A

x-linked recessive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

S/S of G6PD Deficiency

A
  • heinz bodies
  • jaundice
  • triggers (fava beans, asa, abx, and azo)
  • dark urine
  • abd or lumbar pain
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Treatment of G6PD deficiency

A
  • avoid triggers
  • folic acid supplementation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

s/s of ITP

A
  • generally healthy kid
  • petechiae
  • purpura
  • ecchymoses
  • mucosal bleeding
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

diagnosis of ITP

A

isolated thrombocytopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

treatment of ITP

A
  • watchful waiting at first
  • severe: steroids
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

etiology of iron deficiency anemia

A
  • deficient intake
  • chronic blood loss
  • decreased absorption
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

s/s of iron deficiency anemia

A
  • pallor
  • fatigue
  • pica
  • brittle nails
20
Q

treatment of iron deficiency anemia

A

iron replacement

21
Q

presentation of non-hodgkin lymphoma

A
  • painless lymphadenopathy
  • constitutional symptoms
22
Q

diagnosis of non-hodgkin lymphoma

A

lymph node biopsy

23
Q

treatment of non-hodgkin lymphoma

A

single or multidrug chemo

24
Q

presentation of hodgkin lymphoma

A
  • painless lymph mass
  • reed sternberg cells
  • constitutional symptoms
25
Q

treatment of hodgkin lymphoma

A

multidrug chemo

26
Q

presentation of multiple myeloma

A
  • bone pain
  • pathologic fractures
  • plasmacytomas
27
Q

diagnosis of multiple myeloma

A
  • RBC rouleaux
  • lytic bone lesions
28
Q

management of multiple myeloma

A
  • induction chemo
  • stem cell transplant
  • radiation
29
Q

etiology of sickle cell anemia

A

autosomal recessive

30
Q
A
31
Q

diagnosis of sickle cell

A
  • sickle cells
  • howell jolly bodies
  • HbF
32
Q

treatment of sickle cell anemia

A
  • folic acid supplementation
  • hydroxyurea
  • hydration, oxygen, pain control
  • definitive: stem cell transplant
33
Q

etiology of alpha thalassemia

A

gene deletions leading to reduced alpha chain synthesis

34
Q

s/s of alpha thalassemia

A
  • target cells
  • inclusion bodies
35
Q

Treatment of alpha thalassemia

A
  • trait: none
  • hemoglobin H: folic acid
  • hydrops fetalis: typically lethal in womb
36
Q

s/s of beta thalassemia

A
  • chipmunk face
  • target cells
  • thin long bones
  • pathologic fractures
37
Q

treatment of beta thalassemia

A

bone marrow transplant

38
Q

etiology of TTP

A

adamts13

39
Q

s/s of TTP

A
  • AMS
  • fatigue
  • petechiae
  • fever
  • dark urine
40
Q

diagnosis of TTP

A
  • schistocytes
  • negative coombs test
41
Q

treatment of TTP

A

plasma exchange with FFP

42
Q

presentation of B12 deficiency

A
  • anemia
  • fatigue
  • neuropathy
  • glossitis
  • angular cheilosis
43
Q

diagnosis of B12 deficiency

A
  • increased methymalonic acid
  • increased homocysteine
44
Q

treatment of B12 deficiency

A

replacement

45
Q

s/s of folic acid deficiency

A
  • anemia
  • glossitis
  • fatigue
  • anglar cheilosis
  • NO neuropathy
46
Q

treatment of folic acid deficiency

A

replacement