Internal Med Endocrine Flashcards

1
Q

etiology of acromegaly

A
  • adenoma (Of pituitary?)
  • GH excess
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2
Q

s/s of acromegaly

A
  • large forehead
  • large hands
  • cardiomegaly
  • large nose
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3
Q

diagnosis of acromegaly

A

GH suppression test

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4
Q

treatment of acromegaly

A
  • surgical resection
  • somatostatin analogues (ocreotide)
  • dopamine agonists (bromocriptine or cabergoline)
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5
Q

etiology of addisons disease

A

autoimmune

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6
Q

s/s of addisons disease

A
  • hyperpigmentation
  • hyponatremia
  • hypotension
  • abdominal pain
  • change in body hair
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7
Q

diagnosis of addisons disease

A
  • rapid ACTH stimulation
  • plasma cortisol levels
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8
Q

treatment of Addison’s disease

A
  • hydrocortisone
  • fludrocortisone
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9
Q

etiology of cushing disease

A
  • exogenous steroids
  • tumor
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10
Q

s/s of cushing disease

A
  • central obesity
  • moon face
  • buffalo hump
  • striae
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11
Q

diagnosis of cushing disease

A
  • dexamethasone suppression
  • 24 urine free cortisol
  • late night salivary cortisol
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12
Q

treatment of cushing disease

A
  • stop exogenous cortisol
  • remove tumor
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13
Q

etiology of diabetes insipidus

A
  • primary: autoimmune
  • secondary: damage to hypothalamus or pituitary stalk
  • nephrogenic: defect in kidney tubules
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14
Q

s/s of diabetes insipidus

A
  • thirst
  • polyuria
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15
Q

diagnosis of diabetes insipidus

A
  • fluid restriction
  • vasopressin challenge test
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16
Q

treatment of diabetes insipidus

A

desmopressin

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17
Q

etiology of hypercalcemia

A
  • malignancy
  • hyperparathyroidism
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18
Q

s/s of hypercalcemia

A
  • stones
  • bones
  • groans
  • psych overtones
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19
Q

treatment of hypercalcemia

A

-fluids
-loop diuretics

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20
Q

etiology of hypernatremia

A
  • loss of body water
  • increased sodium intake
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21
Q

s/s of hypernatremia

A

neuro s/s

22
Q

treatment of hypernatremia

A

fluids

23
Q

etiology of hyperparathyroidism

A

parathyroid adenoma

24
Q

s/s of hyperparathyroidism

A

-sx related to hypercalcemia

25
Q

diagnosis of hyperparathyroidism

A
  • elevated PTH
  • elevated urine calcium
26
Q

treatment of hyperparathyroidism

A
  • if asx: monitor
  • if sx: parathyroidectomy
  • sensispar
27
Q

etiology of hyperthyroidism

A

autoimmune

28
Q

s/s of hyperthyroidism

A
  • tachycardia
  • palpitations
  • weight loss
  • diaphoresis
  • heat intolerance
29
Q

diagnosis of hyperthyroidism

A
  • labs (low TSH, high T3, T4)
  • TSI antibodies
30
Q

treatment of hyperthyroidism

A
  • methimazole
  • PTU
  • beta blockers
31
Q

etiology of hypocalcemia

A
  • hypoparathyroidism
  • vitamin d deficiency
  • CKD
32
Q

s/s of hypocalcemia

A
  • chvostek
  • trosseau
  • cramps
  • dysrhythmias
33
Q

treatment of hypocalcemia

A

calcium supplement

34
Q

etiology of hyponatremia

A
  • overhydration
  • excess Na loss
35
Q

s/s of hyponatremia

A

neuro s/s

36
Q

treatment of hyponatremia

A
  • fluid restriction
  • hypertonic saline
37
Q

etiology of hypoparathyroidism

A
  • autoimmune
  • acquired
38
Q

s/s of hypoparathyroidism

A

hypocalcemia sx

39
Q

treatment of hypoparathyroidism

A
  • calcium supplementation
  • Mag supplement if low
  • vitamin D
  • forteo
40
Q

Etiology of Paget’s Disease

A

accelerated bone remodeling

41
Q

s/s of pagets disease

A
  • mostly asx
  • bone pain
  • fractures
42
Q

diagnosis of pagets disease

A
  • elevated alk phos
  • lytic lesions on xray
43
Q

treatment of pagets disease

A

bisphosphonates

44
Q

s/s of pheochromocytoma

A
  • palpitations
  • HA
  • diaphoresis
  • HTN
45
Q

Diagnosis of pheochromocytoma

A

plasma free metanephrines

46
Q

Treatment of pheochromocytoma

A

surgical removal

47
Q

S/S of thyroid cancer

A
  • single nodule
  • often asymptomatic
48
Q

most common thyroid cancer

A

Papillary carcinoma

49
Q

diagnosis of thyroid cancer

A
  • US
  • biopsy
50
Q

treatment of thyroid cancer

A

thyroidectomy