Integumentary Terms (Path Final) Flashcards
1
Q
Acantholysis
A
loss of cohesion btwn keratinocytes caused by the breakdown of intercellular bridges
2
Q
Acanthosis
A
thickening of the spinous cell layer (stratum spinosum) of the epidermis
3
Q
Acral
A
distal parts of the extremities
4
Q
Anagen
A
phase in which hair synthesis takes place
5
Q
Anaplasia
A
lack of cellular differentiation & organization, a feature of neoplastic cells
6
Q
Angioedema
A
vascular reaction involving the deep dermis or subcutis & consistitng of edema manifested as giant wheals & caused by dilation & increased permeability of capillaries
7
Q
Angioedema is a deeper version of what?
A
Urticaria
8
Q
Ballooning degeneration
A
marked intracellular fluid accumulation in the cells of the epidermis
9
Q
Blister
A
localized collection of fluid usually in or beneath the epidermis
10
Q
A blister is also known as what? (2)
A
vesicle or bulla
11
Q
Bulla
A
Blister > or = to 1.0 cm
12
Q
Carinoma in situ
A
malignant neoplasm of epithelial origin that has not invaded through the basement membrane
13
Q
Catagen
A
Transition phase of the hair cyle; btwn growth & resting phase
14
Q
Cellulitis
A
acute bacT infection of the dermis & subcutis that spreads to surrounding soft tissues
15
Q
What are the characteristics of Cellulitis? (6)
A
erythema warmth swelling pain fever enlarged lymph nodes
16
Q
What is often the source of infection for Cellulitis?
A
penetrating wound in the area of infection
17
Q
Comedo (pl= comedones)
A
plug of follicular stratum corneum & dried sebum in a hair follicle that leads to follicular distention
18
Q
Cornification
A
Production of stratum corneum by terminal epidermal differentiation
19
Q
Material formed by drying of exudate or secretion on the skin surface
A
crust
20
Q
Small molecular wt. protein (< 30 kD) that are mediators of inflammation & growth
A
Cytokines
21
Q
Naturally pigmented black or brown mycelium or conidium
A
Dematiaceous
22
Q
Infection of the stratum corneum of the epidermis, hair or claws with fungi of the genera Microsporum, Epidermophyton, or Trichophyton
A
Dermatophytosis
23
Q
Noninflammatory lesion of the skin
A
Dermatosis
24
Q
Dandruff
A
Detritus
25
Abnormal, premature or imperfect keratinization
Dyskeratosis
26
Abnormal development
Dysplasia
27
Shedding of hair
Effluvium
28
Degeneration of dermal C.T. leading to accumulation of elastotic fibers
Elastosis
29
When is elastosis sometimes seen?
w/ solar dermatitis
30
peripheral expanding ring of scale
Epidermal Collarette
31
Inflammation of the epidermis
Epidermitis
32
Separation of the epidermis from the dermis
Epidermolysis
33
Have a predilection to enter the epidermis or other epithelial structures as seen with cutaneous T-cell lymphoma (mycosis fungoides)
Epidermotropic or Epitheliotropic
34
Loss of the superficial layers of the epidermis
Erosion
35
Rapid development of skin lesion associated w/ redness
Eruption
36
Redness of the skin caused by congestion of capillaries
Erythema
37
Superficial loss of epidermal layers caused by physical trauma (scratching)
Excoriation
38
Shedding of layers or scales
Exfoliation
39
Stage in which old hairs are shed in the hair cycle
Exogen
40
Fluid, cells or debris from blood vessels deposited in or on other tissues
Exudate
41
Cleft or groove
Fissure
42
Inflammation of a hair follicle
Folliculitis
43
Circumscribed, painful node (accumulation of pus) in the dermis 2ry to follicular rupture
Furuncle
44
Rupture of follicles usually caused by inflammation, distention &/or trauma to entry of follicular contents into the dermis
Furunculosis
45
A genetically determined disorder of the skin
Genodermatosis
46
smooth skin, hairless skin
Glabrous
47
A localized, tumor-like malformation of mature cells & tissue that includes normal components of the organ in which the hamartoma arises but that is disorganized, present in excess & sometimes larger than normal.
Hamartoma
48
Is a hamartoma a true neoplasm?
No, b/c it involves the proliferation of more than one cell type & often includes the development of complex structures such as arteries or follicles
49
Intracellular fluid accumulation in cells of the basal epidermis
Hydropic degeneration
50
Thickening of the stratum corneum
Hyperkeratosis
51
Incomplete development
Hypoplasia
52
Less hair than normal
Hypotrichosis
53
Congenital skin disorder in which the skin is thickened by scales (hyperkeratosis) that can crack into plates resembling fish scales
Ichthyosis
54
Bacterial dermatitis characterized by pustules
Impetigo
55
Slow growing; persistent ulcers on the lips of cats
Indolent
56
Hardening of the skin as a result of inflammation or fibrosis
Indurated
57
Inflammation arranged in a layer close to & often obscurring the epidermal-dermal jxn & w/ vacuolated & sometimes apoptotic basal cells. Can be mild or extensive
Interface
58
Dermatitis that develops b/c of friction btwn apposing skin surfaces
Intertrigo
59
Epidermal cells that synthesize keratin & comprise more than 90% of epidermal cells
Keratinocytes
60
Uncommon to rare circumscribed paular, plaque-like, or linear focus of proliferative keratinocytes covered by thick stratum corneum
Keratosis (pl. Keratoses)
61
What can cause keratosis? (2)
Sun exposure
| Idiopathic
62
An intense focal folliculitis usually caused by a dermatophyte infection
Kerion
63
Intraepidermal dendritic APCs
Langerhans' cells
64
Thickening of skin w/ accentuation of skin creases caused by marked acanthosis
Lichenification
65
Generally refers to a dense zone of dermal inflammation parallel to the epidermis usually w/o basal cell injury
Lichenoid
66
Uncommon to rare, often idiopathic, single or grouped papules, plaques or papillomatous foci covered by scale
Lichenoid dermatosis
67
Histologically composed of epidermal hyperplasia, lichenoid lymphoplasmacytic dermal inflammation, hyperkeratosis & parakeratosis
Lichenoid dermatosis
68
Flat, circumscribed lesion of altered skin color
Macule
69
Dark granular pigment produced by melanocytes that is responsible for the brown coloration of hair, skin & other tissues
Melanin
70
Macrophage containing ingested melanin
Melanophage
71
A neuroendocrine cell found in the stratum basale
Merkel Cell
72
Glycosaminoglycan (GAG), normal component of intercellular ground substance of the deris; consists of protein bound to hyaluronic acid
Mucin
73
A mass of hyphae
Mycelium
74
Slowly progressive infection of the cutaneous & SQ tissue, fascia & sometimes underlying bone caused by traumatic implantation of actinomycetes or fungi
Mycetoma
75
Traumatic implantation of actinomycetes
Actinomycotic mycetoma
76
Traumatic implantation of fungi
Eumycotic mycetoma
77
Non-pitting edema of the skin b/c of abnormal deposits of mucin in the dermis
Myxedema
78
Ac acute lif-threatening subtype of cellulitis usually caused by Strep. infection & toxin production. Located w/in the SQ fat & fascial planes
Necrotizing fasciitis
79
What are the appearance of the gross lesions of necrotizing fasciitis?
Painful, hot & swollen areas w/ entensive exudation & necrosis
80
What can Necrotizing fasciitis progress to?
can progress rapidly to shock
81
Circumscribed malformation of the skin assumed to be of congenital or inherited origin & consisting of any component of the skin
Nevus
82
Which term is preferred over nevus?
Hamartoma
83
A circumscribed, solid elevation of skin (> 1cm)
Nodule
84
Abnormal formation of the claw
Onychodystrophy
85
Sloughing of the claws
Oncychomadesis
86
Inflammation of SQ adipose tissue
Panniculitis
87
Circumscribed, solid elevation of skin (< 1cm)
Papule
88
Retention of pyknotic nuclei in epidermal cells of the stratum corneum
Parakeratosis
89
Inflammation of skin around the claws
Paronychia
90
A localized intraepidermal collection of neoplastic lymphocytes characterisitic of epitheliotropuc lymphoma (mycosis fungoides)
Pautrier's Microabscess
91
A group of cutaneous dz's associated w/ blistering
Pemphigus
92
Mycotic dz caused by pigmented fungi of a variety of genera & species that do not form sclerotic bodies or gransules
Phaeohyphomycosis
93
Melanin pigment w/in dermal macrophages or free in the dermis developing via injury to pigment containing basal layer cells
Pigmentary Incontinence
94
Flat-topped, solid elevation in the skin that occupies a relatively large surface area in comparison w/ its height (> 1 cm)
Plaque
95
Itching
Pruritus
96
Small, circumscribed accumulation of pus w/in the epidermis or w/in a hair follicle
Pustule
97
Pyogenic bacterial infection of the skin
Pyoderma
98
Term from human med; used to define an ulcerative basal cell carcinoma
Rodent ulcer
99
Which term is often incorrectly used in Vet Med to describe an indolent ulcer affecting the lips of cats?
Rodent Ulcer
100
Thin, platelike accumulation of stratum corneum on the surface of the skin
Scale
101
Nonspecific term for C.S. of scaling, crusting & greasiness
Seborrhea
102
More specific term, applied to inherited cornification disorders
Primary seborrhea
103
Secretion of the sebaceous glands
Sebum
104
Intercellular edema, which, by widening of the intercellular space & stretching of the "intercellular bridges" creates a sponge-like appearance to the epidermis
Spongiosis
105
Resting phase of the hair cycle
Telogen
106
Full thickness loss of the epidermis w/ extension into the dermis
Ulcer
107
Usually transient vascular rxn in the upper dermis consisting of edema manifested clinically as wheals; more superficial version of angioedema
Urticaria
108
What is another term for wheals?
Hives
109
Small blister w/in the epidermis or at or below the dermal-epidermal interface (<1.0 cm)
Vesicle
110
Long, coarse hair located above the nose
Vibrissa
111
Acquired disorder characterized by circumscribed areas of depigmentation in the skin
Vitilido
112
Smooth, circumscribed, slightly elevated area on the skin caused by dermal edema
Wheal
113
Unicellular budding fungus
Yeast
