Path Lab Midterm Flashcards
What species is the most common to get squamous cell carcinoma and where?
HORSE - penis/eyelid
dog/cat - skin
cow - eye/vulva
What is the round hyaline red stained structure in a squamous cell carcinoma?
keratin pearl
What is not a tumor that is seen on bovine eyes?
dermoid (adnexa present) - hyperplasia
What nailbed tumor is benign?
subungual keratoacnthoma - no breach of basal lamina
What 2 nail bed tumors are malignant?
subungual squamous cell carcinoma
subungual malignant melanoma
What species do not get papillomas?
cats
What species do fibropapillomas develop and where?
bovine penis and vagina (in young animals)
What are the 2 forms of papillomas in dogs?
oral papillomas
cutaneous papillomas
Where do papillomas occur on the horse?
nose and lips in young horses, regress quickly
Which species do not get fibromas?
dogs
What species get fibrosarcomas most commonly?
cats - virus, inflammation, vaccine
What causes fibrosarcomas in dogs?
spiro cerca lupi
What tissue is affected by rhabdomyomas?
striated muscle
What species get lipomas?
dog, cat, horse
Where do lipomas arise in horse? How can it be dangerous?
mesentary - death by strangulation
What is the origin of histiocytomas?
cutaneous macrophage (langerhan cells)
What does a histocytoma become in a dog?
button tumor - benign but grows fast
What are the important characteristics of TVT (transmissable venereal tumor)?
- high incidence in temperate areas
- grows as graft
- locally invasive
What species gets melanoma/melanocytomas?
DOG - benign on skin, malignant on mucousa
gray horse - perianal/perineal
mini pigs
What species most commonly get mast cell tumors and where?
dog - skin, always eosinophils
cat - SPLEEN
What are the 3 forms of mast cell tumors in cats?
cutaneous - histiocytic, mast cell form
visceral - spleen, ulcers (can be in GI)
GI - no ulcers
What stain is used for poorly granulated mast cells in tumors?
toluidin blue
What is the most common neoplasia in animals?
lymphosarcoma
What 5 forms of lymphosarcoma do dogs get and what do they cause?
Multicentric form and mediastinal form - both cause hypercalcemia
Alimentary
cutaneous
extranodal
How much of hemopoietic tumors do lymphosarcomas cause in cats?
90%
What are lymphosarcomas caused by in cats?
FeLV
What form of lymphosarcomas do cats not get?
cutaneous
What are the 3 forms of sporadic lymphosarcomas in cattle?
calf, thymic, skin
What is the adult form of lymphosarcoma in cattle?
enzootic leukosis - BLV
What are the 3 forms of plasma cell tumors?
cutaneous plasmacytoma - old dogs, benign
extramedullary plasmacytoma - old dogs, rectal mucosa
multiple myeloma - rare, involvement of BM, hypercalcemia
What species get hamangiosarcomas and where?
dog - common, spleen
cat - liver
What are the clinical signs of hemangiosarcoma
50% die from sudden rupture
in heart - RA
thrombocytopenia = DIC in dog
What glands are involved most commonly for mammary gland tumors in cats?
2 anterior ones
What is a clinical sign of adenocarcinoma?
hypercalcemia (PTH like substance)
What describes a “peri anal” gland tumor?
dogs - hepatoid looking
What are seminomas associated with?
dog - cryptorchidism
Which species get leydig cell tumors? What do they look like?
old dog - rosettes around vessels
What species gets sertoli cell tumors and what do they cause?
dogs - feminization
What are ovarian tumors made of and what do they cause?
granuloma cell tumor
cow/horse - nymphomania, masculinization
Which species get uterus adenomas?
rabbit, cow
