integumentary system Flashcards
what is the integumentary system is composed of:
-Skin
-Hair
-Nails
-sweat glands
-Sebaceous glands
-Mammary glands
what are the functions of the skin?
- Thermoregulation
- Blood reservoir
- Protection
- Cutaneous sensations
- Excretion and absorption
- Synthesis of vitamin D
what is gross anatomy of te integumanetary systen
- large organ composed of all 4 tissues
- 22 sq feet
- 0.5 mm - 5.0 mm thick
- thicker on feet and palms - weights approximately 10 LBS
what are the two layers of the skin?
- epidermis is epithelial tissue only (can see)
- dermis is a layer of connective tissue, never & muscle
what is subcutaneous tissue?
- Sub Q, hypodermis is a layer of adipose and areolar tissue
what is the cutaneous membrane made out of?
- epidermis (thin)
- dermis
what are the accessory structures?
- hair follicles
- exocrine glands
- nails
what is the overall structure of the integumentary system
- cutaneous membrane
- epidermis
- superficial epithelium - Dermis
- underlying connective tissue
- deep to fermis is the hypodermis
- also known as sub q - hypodermis
what is the function of the epidermis
- Protects dermis from
trauma, chemicals - Sensory receptors
detect touch, pressure,
pain, and temperature - Synthesizes vitamin D
- Prevents entry of
pathogens - Controls skin
permeability, and
prevents water loss
What is the function of the hair follicles?
- Produce hairs that
provide delicate
touch sensations
on general body
surface - produce hairs that protect the skull
what is the function of exocrine glands?
- assists in thermoregulation
- excrete waste
- lubricates epidermis
What is the function of the nails?
- protect and supports tips and fingers and toes
overview of epidermis?
- Stratified squamous epithelium
- Contains no blood vessels
- 4 types of cells
- 5 distinct strata (layers) of cells
what are the layers of the epidermis
- Stratum corneum
- Stratum lucidum
- Stratum granulosum
- Stratum spinosum
-Stratum basale
COME
LETS
GET
SUN
BAKED
what are the cells of the epidermis
- Keratinocytes–90%
- produce keratin - Melanocytes—–8 %
- produces melanin pigment
- melanin transferred to other cells with long cell processes - Langerhan cells
- from bone marrow
- provide immunity - Merkel cells
- in deepest layer
- form touch receptor with sensory neuron
what does the stratum Basale
- Deepest single layer of cells
- Called stratum germinativum
- Combination of merkel cells, melanocytes, keratinocytes & stem cells that divide repeatedly
- Cells attached to each other & to basement membrane by desmosomes & hemidesmosomes
what’s in the second layered the Stratum spinosum
- 8 to 10 cell layers held together by desmosomes
- During slide preparation, cells shrink and look spiny
- Melanin taken in by phagocytosis from nearby melanocytes
what’s in the stratum grandulosum
- 3 - 5 layers of flat dying cells
- Show nuclear degeneration
- Contain dark-staining keratohyalin granules
- Contain lamellar granules that release lipid that repels water
what’s in the stratum lucidum
- Seen in thick skin on palms & soles of feet
- Three to five layers of clear, flat, dead cells
- Contains precursor of keratin
what’s in the Stratum Corneum?
- 25 to 30 layers of flat dead cells filled with keratin and surrounded by lipids
- Continuously shed
- Barrier to light, heat, water, chemicals & bacteria
- Friction stimulates callus formation
what is the process of keratinzation & epidermal growth
- Stem cells divide to produce keratinocytes
- As keratinocytes are pushed up towards the surface, they fill with keratin
- 4 week journey unless outer layers removed in abrasion
- Hormone EGF (epidermal growth factor) can speed up process
what are skin grafts?
- New skin can not regenerate if stratum basale and its stem cells are destroyed
- Skin graft is covering of wound with piece of healthy skin
- autograft from self
- isograft from twin
- autologous skin
- transplantation of patients skin grown in culture
what layer of skin cannot regenerate if damaged?
- stratum Basale
- & it’s stem cells
what are the two major regions of the dermis?
- papillary region
- reticular region
what is the dermis composed of?
- Connective tissue layer composed of collagen & elastic fibers, fibroblasts, macrophages & fat cells
- Contains hair follicles, glands, nerves & blood vessels
what is the papillary region composed of?
- Top 20% of dermis
- Composed of loose CT & elastic fibers
- Finger like projections called dermal papillae