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CVA > Integumentary System > Flashcards

Integumentary System Flashcards

1
Q

4 types of tissues

A
  1. Epithelial
  2. Connective
  3. Nervous
  4. Muscle
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2
Q

What are the two different types of intercellular attachment categories and junctions in each category?

A
  1. Communicating junctions (gap)
  2. Adhering junctions (tight, desmosome, plasmodesmata???)
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3
Q

What are the functions of the integumentary system?

A
  1. Protects the body
  2. Communication (blushing, coloring, warning)
  3. Vitamin D synthesis
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4
Q

What does the integumentary system protect the body from?

A

pathogens, abrasions, uv radiation, desiccation

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5
Q

What do gap junctions do?

A

Allow rapid communication - link cytoplasm of one cell to another with connexin channel proteins (found in heart)

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6
Q

What do tight junctions do?

A

Limit transportation - proteins fuse plasma membranes together, intercellular space sealed shut - like pants pockets/seam (found in blood-brain barrier and intestinal/bladder cells)

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7
Q

What do desmosomes do?

A

Relates to the cytoskeleton which keeps structure of the cell - form strong cohesive tissue from falling apart - strongest of all attachments (skin) (gutter rivet)

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8
Q

Define desiccation

A

drying out

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9
Q

Do fish have a keratinized epidermis? Why or why not?

A

Fish lack a keratinized epidermis because they live in the water

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10
Q

What are the 2 types of unicellular epithelial glands in fish?

A
  1. Club cells - secrete alarm chemicals (a school of fish one is eaten the others hide)
  2. Goblet/mucus cells - secrete mucin (reacts with water to make mucous)
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11
Q

What are the two types of fish scales?

A
  1. dermal bony scales (Actinopterygii)
  2. placoid scales (Chondrichthyes)
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12
Q

Compare and contrast types of fish scales

A

Dermal bony: scale does not pierce epidermis - scales are completely covered by tissue - none is exposed to outside environments in Actinopterygii

Placoid scales: scales and teeth form from the dermis - scales pierce epidermis - (sharks and Chondrichthyes

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13
Q

Is the keratinized epidermis the same across species?

A

No. Fish do not have a keratinized epidermis and the thickness will fluctuate through species (amphibians have thinner)

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14
Q

What 3 parts make up the cytoskeleton?

A
  1. microtubules
  2. actin
  3. intermediate filaments
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15
Q

What is a hemidesmosome and where is it located?

A

Located on the basement membrane - it attaches to cytoskeleton of epidermis but connective tissue on basement membrane

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16
Q

What is the benefit of the mucous cuticle?

A
  1. hydrodynamics (maneuver through water)
  2. pathogens (protective keep out bacteria)
  3. repugnant chemicals
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17
Q

What gives the shark the ability to move without wrinkling and not taut skin?

A

helical cross-fibering of collagen

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18
Q

What are the two layers of shark skin?

A
  1. stratum laxum (little collagen)
  2. stratum compactum (packed dense compact collagen)
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19
Q

What is the amount of glands and keratinization in amphibians?

A
  1. low keratinization to the epidermis
  2. glandular secretions to keep skin moist
  3. no dermal scales
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20
Q

How does Eastern newt skin vary?

A

Aquatic larvae - active mucus glands - no keratinization
Terrestrial juvenile - moderate keratinization (turn red)
Aquatic adult - weak keratinization - active mucus glands

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21
Q

What organisms (fish/amphibians) have unicellular glands and what have multicellular?

A

fish = unicellular (goblet)
amphibian = multicellular (poison)

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22
Q

What are the 2 layers of amphibian epidermis?

A
  1. stratum corneum (thin)
  2. stratum basale (layer of epidermis that does mitosis)
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23
Q

What is a xeric habitat?

A

dry habitat

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24
Q

What is ecdysis and what triggers it?

A

shedding of reptile skin all at once triggered by ecdysone (hormone)

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25
Q

What are the steps of ecdysis:

A
  1. stratum basale grows a new epidermis
  2. lysosomes trigger autolysis - sep old layer from new
  3. new layer is now exposed
    (all triggered by ecdysone)

Rest -> Renewal -> Shed -> Repeat

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26
Q

What is an example of a reptile integumentary gland?

A

femoral scent glands of lizards (fence lizards)

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27
Q

Layers of bird epidermis:

A
  1. stratum corneum (weak)
  2. transitional layer
  3. stratum basale
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28
Q

Compare and contrast body/wing of chicken/bird vs. legs

A

The body of a bird is weakly cornified (any area covered with feathers) vs. the increased cornified epidermal scales on the legs

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29
Q

What are the 2 types of bird glands?

A
  1. uropygial gland
  2. salt glands
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30
Q

Uropygial gland

A

oil gland right above tail feathers - used in preening - move lipid wax all over feathers which causes water to roll off back

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31
Q

Salt glands

A

are found in marine birds - excretes excess salt - located by eye

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32
Q

What are the 2 mechanisms of bird coloration?

A
  1. pigment with chromatophores
  2. structural coloration ( light reflectance)
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33
Q

Where are the chromatophores located?

A

stratum basale & dermis

34
Q

List the 4 types of pigments of birds and their chromatophores and color:

A
  1. carotenoids - erythrophores - red
  2. carotenoids - xanthophore - yellow
  3. phaeomelanin - melanophore - brown
  4. eumelanin - melanophore - black
35
Q

What causes a flamingo to turn pink?

A

flamingos are born white, but they receive dietary carotenoids from the food they eat which get embedded in feathers

36
Q

What are some birds that use structural coloration?

A

hummingbird, peacock, starling

37
Q

How is a bird white?

A

they do not have chromatophores - all light is reflected

38
Q

What makes birds blue?

A

There is no blue pigment - it is structural coloration - feathers are actually brown - blue wavelengths are reflected through light

39
Q

Structural formation of blue feather structure

A
  1. keratin cortex
  2. spongy layer (big air space)
  3. black melanin layer
40
Q

Layers of mammal integument skin

A
  1. epidermis
  2. dermis
  3. hypodermis (subcutaneous level)
41
Q

What does the hypodermis consist of?

A
  1. adipose cells (insulation)
  2. arteries & veins (run along boundary of dermis)
  3. sensory nerve fibers
  4. areolar connective tissue
42
Q

Areolar connective tissue

A

“packing tissue” of body - holds material in place

43
Q

What does transdermal mean and what is an example of this?

A

across the dermis - nicotine patches (quit smoking)

44
Q

What are the 2 layers of the mammal dermis and what is the thickness of each?

A
  1. papillary layer (thin)
  2. reticular layer (thick)
45
Q

What is the total thickness of the average dermis?

A

1-2 mm thick

46
Q

What is in the papillary layer?

A

areolar connective tissue, sensory neurons, capillaries

47
Q

What is in the reticular layer?

A

mesh of collagen (gives structure)
elastin (gives flexibility)

48
Q

What is the role of papillary capillaries?

A

blushing, cooling off (thermoregulation) - sends blood close to the surface to expel heat

49
Q

What kind of immune activity is in the dermis?

A

macrophages destroy pathogens

50
Q

Where is the attachment of dermis & epidermis?

A

basement membrane

51
Q

How many layers is the basement membrane and what are they?

A

2 - basal lamina (top) & reticular lamina (bottom)

52
Q

What are the layers of the epidermis?

A
  1. stratum corneum
  2. stratum lucidum
  3. stratum granulosum
  4. stratum spinosum
  5. stratum germinativum/basale
53
Q

What epidermal layer is in mammal thick skin only?

A

stratum lucidum (most likely not actual layer)

54
Q

Which epidermal layer in mammals is mitotically active?

A

stratum germinativum/basale

55
Q

What are the cells found w/in the mammal epidermis?

A
  1. Keratinocytes
  2. Melanocytes
  3. Langerhans cells
  4. Merkel cells
56
Q

Stratum germinativum

A

runs up and down papillae (1 cell thick - makes new cells predominately keratinocytes - also melanocytes and Merkel cells

57
Q

Stratum spinosum

A

primarily keratinocytes - there are some melanocyte processes and Langerhans cells - it is spiny because stain causes cells to desiccate and shrink

58
Q

Stratum granulosum

A
  1. cells are starting to die
  2. organelles diseintegrate
  3. plasma membrane thickens
  4. cells flatten
  5. secrete lipids

grainy look comes from keratohyalin granules that link keratin protein fibers by cross-linkage

59
Q

Stratum corneum

A
  1. dead keratinocytes full of keratin fibers
  2. dry surface unsuitable for many bacteria
  3. limits transepidermal water loss
  • what we see
60
Q

What are three accessory structures in the integument?

A
  1. hair
  2. sebaceous glands
  3. sweat glands
61
Q

What are all the sweat gland types:

A
  1. apocrine (2 types: ceruminous & mammary)
  2. eccrine (aka merocrine)
62
Q

Sebaceous gland

A

moisturizes hair with oily secretion of sebum goes to hair shaft

  • holocrine secretion
  • arrector pili contraction squeezes gland and sebum secreted onto hair & skin
  • keeps hair from being brittle
  • inhibits bacterial growth
63
Q

Which type of secretion do apocrine & eccrine glands use?

A

apocrine & eccrine

64
Q

Which type of secretion do sebaceous glands use?

A

holocrine

65
Q

What two glands are on the hair shaft?

A

sebaceous & apocrine

66
Q

Eccrine/Merocrine sweat glnds

A

cause sweating - highly dense lots on hand sand feet which is beneficial for grip.

  • merocrine secretion using myoepithelial cells
  • watery secretion released onto skin
67
Q

What are two examples of myoepithelial contraction in glands?

A
  1. mouth when eating something sour (lemon)
  2. milk letdown
68
Q

Apocrine sweat glands

A
  • used for communication
  • dense on genitalia, belly button, breast, armpits
  • merocrine secretion using myoepithelial cells
  • viscose, lipid-rich flid
  • release onto hair shaft
  • onset at puberty
69
Q

Two examples of apocrine sweat glands

A
  1. ceruminous glands
  2. mammary glands
70
Q

Ceruminous glands

A
  • only in external auditory canal
  • secretions with sebum to form cerumen
71
Q

Functions of cerumen:

A

Ear wax
1. antibiotic & antifungal properties
2. traps dirt, dust, debris

72
Q

Functions of arrector pili muscle:

A
  1. communication (goose bumps, hair standing up when scared to look threatening)
  2. conserve heat when cold ( arrected hairs trap air and body heat warm up)
73
Q

What is epidermal invagination

A

the epidermis is pushed way down deep into dermis (hair matrix - as mitosis occurs cells continue to be pushed upwards)

74
Q

What are the “composite-like” components of a hair?

A
  1. cuticle (flattened cells full of keratin - outer)
  2. cortex - cells with stiff keratin fibers
  3. medulla - cells with soft, flexible keratin fibers
75
Q

What are split-ends?

A

The cuticle wears away and the rods of the medulla frizz out (like a broken frayed wire)

76
Q

What causes different hair colors?

A

melanocytes in cortex

77
Q

What are the different melanocytes and what colors do they form in hair?

A
  1. phaeomelanin (red, yellow)
  2. eumelanin (brown, black)
78
Q

Compare albinism & melanism:

A

albinism- highly reduced melanin production
melanism - increased melanin production (black squirrels)

79
Q

Melanosome transfer contrasts in different skin colors (layers)

A
  1. light-skinned (stratum spinosum, stratum basale)
  2. dark-skinned (stratum granulosum, stratum spinosum, stratum basale)
80
Q

What is different about dark-skinned melanocytes?

A

larger and more active not more in quantity

81
Q

What is the vitamin D-folate hypothesis?

A

Too little - vitamin d synthesis - rickets
Too much - folic acid destruction - male sterility

82
Q

What are 4 things that happen to aging skin?

A
  1. less active stratum basale (epidermis thins, prone to infections)
  2. eccrine sweat glands less active (reduced thermoregulation)
  3. melanocyte activity declines (pale skin, hair turns white/gray)
  4. reduced subQ fat & blood thinners (facilitate easy bruising)

CVA (20 decks)

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