Integumentary System

Question 1

The ____ covers the entire body and is the largest organ accounting for 20% of all body weight. It functions to protect the internal environment from microorganisms, ultraviolet rays and has a variety of receptors to provide feedback to internal structures of the body such as Vitamin D absorption and immune surveillance.

Answer 1

Skin (Integumentary system)

Question 2

The skin is composed of three different layers. the ______ is the outermost defensive layer of skin that is composed of _______ which secretes a scleroprotein that provides protection. This layer also is composed of several smaller layers (Stratum Basale+Stratum Spinosum=Straum Germinativum->Stratum Corneum) that allow for skin renewal via the aforementioned cells. There are also various receptors such as _____ which secretes melanin when exposed to UV light as well as ______ cells which mediate immune responses and ____ cells which allow for touch sensation (See next cards for other layers)

Answer 2

1. Epidermis, 2. keratinocytes, 3. melanocytes, 4. Langerhans, 5. Merkel

Question 3

The middle layer of skin or the ______ is composed of three kinds of connective tissue which include ____, ____ and _____. This layer also contains blood vessels, sweat glands, nerves, hair follicles and lymphatic vessels.

(See next card for other skin layer)

Answer 3

1. Dermis, 2. collagen, 3. elastin/reticulin, 4. gel-like substance

Question 4

The innermost layer of skin or the _______ consists of _____ tissue, but is continuous with the dermis due to collagen running continuously through the body tissues.

Answer 4

1. hypodermis, 2. adipose

Question 5

The _______ _____ in the dermis regulates body temperature by opening and closing in conjunction with heat loss via sweating.

Answer 5

Arteriovenous anastomoses

Question 6

______ are round firm elevated scars that result from excessive deposition of fibroblast based extracellular matrix proteins that can cause inflammation and fibrosis due to high metabolic rates.

Answer 6

Keloids

Question 7

_______ ____ is a limited inflammatory disease that begins as a herald patch and is thought to occur from a herpes-like virus.

Answer 7

Pityriasis rosea

Question 8

HSV skin infections are generally defined as type __ and __ where the former tends to be associated with oral infection while the latter is focused around the genitals. Primary infection involves infecting epithelial cells and moving through sensory nerve endings to the dorsal root where it forms lifelong latency.

Answer 8

1. 1, 2. 2

Question 9

Atopic dermatitis is the most common cause of eczema in ______, more than half of individuals who develop AD also develop ____ and _____ later in life.

Answer 9

1. children, 2. asthma, 3. allergies