Integument Flashcards
Keratinocytes aka?
Skin cells
Vascular supply for epidermis
Dermis
2 layers of dermis
- Papillary layer
2. Reticular layer
Papillary layer of dermis
Dermal ridges or papillae interdigitate with rete pegs of epidermis
5 layers of epidermis
- Stratum corneum
- Stratum lucidum
- Stratum granulosum
- Stratum spinosum
- Stratum basale
Where do nerve endings in the skin occur?
- Hypodermis
- Dermis
- Epidermis
Thickest layer of dermis
Reticular layer
What cells make up the bulk of the epidermis?
Keratinocyes
2 types of tumors arising from keratinocytes
- Squamous cell carcinoma
2. Basal cell carcinoma
3 types of epidermal cells other than keratinocytes
- Melanocytes
- Langerhan’s cells
- Merkel cells
Melanocytes are?
Pigment cells
Langerhan’s cells are?
Antigen-presenting cells
Merkel cells are derived from ____ and associated with?
Neural crest → associated with nerve endings in epidermis
Langerhan’s cells originates from?
Monocytes → migrate to epidermis
Function of Langerhan’s cells
- Phagocytize antigens
- Migrate to lymph nodes
- Present antigen to lymphocytes
Langerhan’s cells are located in?
Mainly in stratum spinosum but found throughout the epidermis and dermis
Melanocytes originate from?
Neural crest
Melanocytes produce?
Melanin
After melanin is produced by melanocytes, what happens?
Transferred to keratinocytes → shield nucleus
Melanoma is?
Melanocyte tumor
Modified keratinocyte in contact with a nerve ending is called?
Merkel cell
Merkel cells are found?
Basal layer of epidermis
4 types of skin glans
- Sebaceous glands
- Sweat glands
- Special glands (usually scent)
- Mammary glands
Sebaceous glands are associated with?
Hair follicles
2 types of sweat glands
- Apocrine
2. Merocrine
Which type of sweat gland empties into hair follicles?
Apocrine
Merocrine sweat glands can be found on what types of skin?
Hairy or non-hairy → do not empty to hair follicles
3 special skin glands in sheep
- Infraorbital
- Inguinal
- Interdigital
Special skin glands in goat
Glands near horn
2 special skin glands in cat
- Submental organ glands
2. Circumoral glands
Special skin gland found in both dog and cat
Supracaudal glands
Glands of anal region are in what 4 species?
- Dog
- Cat
- Ferret
- Skunk
Glands of anal sac do what type of secretion?
Merocrine
Hepatoid glands do what type of secretion?
Do not secrete
What is microscopic evidence of apocrine secretion?
Bubble-like blebs of cytoplasm at apical cell surface
Follicle is continuous with?
Epidermis of surface of skin
Shaft of hair protrudes from?
Surface of skin
The part of the hair embedded in the follicle is called?
Root of the hair
Parts of shaft of hair
- Cuticle
- Cortex (hard keratin)
- Medulla (in thick hair only)
Parts of root of hair
- Cuticle
- Cortex
- Medulla (+/-)