Insulins

Question 1

Insulins

Answer 1

Indications for use: Decreased BS in insuline dependent diabetes and non-insuline dependent diabetes.

Action:

1. Increase glucose transport into most body cells
2. Decrease breakdown of glycogen (glycogenolysis)
3. Decrease formation of new glucose from amino and fatty acids (gluconeogenesis)
4. Increase glycogen synthesis

Question 2

Rapid-Acting:

• lispro (Humalog),
• aspart (Novolog)
• glulisine (Apidra)

Answer 2

**Clear

Onset: within 15 mins

Peak: 1-2 hrs

Duration: 3-4 hours

*Tray needs to be in the room*

Question 3

Long-Acting

• Lantus
• • Levemir*
• • Ultralente*

Answer 3

Onset: 1-2 hrs

Peak: NO PEAK

Duration: 24 hrs Once a day

**decrease risk for hypoglycemia

Question 4

Short-Acting:

• Regular (Humulin R, Novolin R)

Answer 4

**Clear

Onset: 30-60 mins

Peak: 2-4 hours

Duration: 5-7 hours

Question 5

Intermediate acting:

• NPH (Humulin N, Novolin N)
• Lente

Answer 5

**Cloudy

Onset: 2-4 hours

Peak: 4-10 hours

Duration: 10-16 hours

Question 6

Pre-Mixed (Intermidiate and Short-Acting mixtures)

• Humulin 70/30

Answer 6

Onset: 30mins

Peak: 2-12 hrs

Duration: 24 hrs

Question 7

What are S.E of Insulins?

Answer 7

1. Hypoglycemia: cool, clammy skin, nervousness, irritability, blurred or double vision, convulsions.
2. Lipodystrophy: any disturbance of fat metabolism

Question 8

What is written in a typical Insulin Order? (5)

Answer 8

1. Name ofr Insulin
2. Type of Insulin
3. Number of Units to be given
4. Time to be given
5. Route of administration