Antibiotics

Question 1

Beta-Lactam Antibacterials

1. Penicillins
2. Cephalosporins

Answer 1

Purpose: to treat infections caused by gram-positive and gram-negative bacteria

Action: kill bacteria by inhibiting synthesis of bacterial cell wall

Question 2

Penicillins (Beta-Lactam Antibacterials)

Penicillin G​

• penicillin G benzathine (Bicillin)

Penicillin V

• V-cillin
• Penvee K
• ​*Penicillinase-resistant
• (antistaphylococcal) penicillins

​Ampicillins

• amoxicillin (Amoxil, Larotid)

Extended Spectrum (antipseudomonal) Penicillins

Penicillin/Beta-Lactamase Inhibitor Combinations

• (Unasyn, Augmentin, Zosyn, Timentin)

Answer 2

**Use: **Respiratory, GI, and GU infections. Best for Gram (+)

Question 3

Cephalosporins

​1st Generation

• cephalexin (Keflex)
• cefazolin (Kefzol)

​2nd Generation

• cefaclor (Ceclor)
• cefoxitin (Mefoxin)

​3rd Generation

• cefixime (Suprax)
• ceftiaxone (Recephin)
• ​*4th Generation
• cefepime (Maxipime)

Answer 3

**Use: **Best for Gram (-) bacteria.

Question 4

Monobactam

• aztreonam (Azactam)

Answer 4

Use: Active against Gram (-) bacteria. Anaerobic bacteria.

Question 5

Carbapenems

• Primaxin
• Merrem

Answer 5

**Use: **Broad spectrum, bacteriocidal, antimicrobacteria.

• INTRA-ABDOMINAL INFECTIONS
• BACTERIAL MENINGITIS.

Question 6

Aminoglycosides

• gentamicin (Garamycin)

Answer 6

**Purpose: **Treat infections caused by Gram (-) organisms of infections. Bacteriocidal.

S.E:_Ototoxic** **ity, Nephrotoxicity _