Inheritance of Sameness Flashcards

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1
Q

What did Griffith discover about DNA?

A
  • mice with smooth/rough and virulent/non-virulent
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2
Q

What did Avery + coworkers discover about DNA?

A

hypothesized that DNA was responsible for change

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3
Q

What did Hershey and Chase discover about DNA?

A

tagged DNA and found DNA to be the genetic material

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4
Q

What did Watson and Crick discover about DNA?

A

discovered the 4 nucleotides and 4 nitrogenous bases

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5
Q

What are the purines?

A

A+G, 2 rings

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6
Q

What are the pyrimidines?

A

T+C, 1 ring

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7
Q

How do eukaryotes go through cell division?

A

go through mitosis to produce 2 identical daughter cells

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8
Q

How do prokaryotes go through cell division?

A

replicate through binary fission which is what mitosis evolved from

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9
Q

What are the 2 ways through which spindle fibres move?

A
  1. Microtubules attach to the kinetochore which has motor proteins
  2. Microtubules have motor proteins
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10
Q

Where are the 3 checkpoints for cell cycle regulation?

A
  1. G1/beginning of DNA synthesis
  2. G2/mitosis check point
  3. Mitotic spindle checkpoint
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11
Q

What are the 7 phases of mitosis?

A
  1. Interphase
  2. Prophase
  3. Pro-metaphase
  4. Metaphase
  5. Anaphase
  6. Telophase
  7. Cytokinesis
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12
Q

What happens in interphase?

A

G1 (regular function
S (DNA synthesis)
G2 (Prep for mitosis)

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13
Q

What happens in prophase?

A
  • chromosomes condense

- mitotic spindle forms

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14
Q

What happens in pro-metaphase?

A
  • spindles attach to chromosomes
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15
Q

What happens in metaphase?

A
  • spindles align chromosomes at the midpoint
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16
Q

What happens in anaphase?

A
  • sister chromatids separate and move towards the poles
17
Q

What happens in telophase?

A

chromosomes decondense

18
Q

What happens in cytokinesis?

A
  • furrowing (animal cells)

- cell plate (plant cells)

19
Q

What are the 9 stages of DNA replication?

A
  1. Helicase
  2. Topoisomerase
  3. Single Stranded Binding Proteins
  4. Primase
  5. DNA Polymerase 3
  6. DNA Poly. 3 added 5-3
  7. DNA Polymerase 1
  8. Ligase
  9. Telomerase