Inheritance of Sameness Flashcards
What did Griffith discover about DNA?
- mice with smooth/rough and virulent/non-virulent
What did Avery + coworkers discover about DNA?
hypothesized that DNA was responsible for change
What did Hershey and Chase discover about DNA?
tagged DNA and found DNA to be the genetic material
What did Watson and Crick discover about DNA?
discovered the 4 nucleotides and 4 nitrogenous bases
What are the purines?
A+G, 2 rings
What are the pyrimidines?
T+C, 1 ring
How do eukaryotes go through cell division?
go through mitosis to produce 2 identical daughter cells
How do prokaryotes go through cell division?
replicate through binary fission which is what mitosis evolved from
What are the 2 ways through which spindle fibres move?
- Microtubules attach to the kinetochore which has motor proteins
- Microtubules have motor proteins
Where are the 3 checkpoints for cell cycle regulation?
- G1/beginning of DNA synthesis
- G2/mitosis check point
- Mitotic spindle checkpoint
What are the 7 phases of mitosis?
- Interphase
- Prophase
- Pro-metaphase
- Metaphase
- Anaphase
- Telophase
- Cytokinesis
What happens in interphase?
G1 (regular function
S (DNA synthesis)
G2 (Prep for mitosis)
What happens in prophase?
- chromosomes condense
- mitotic spindle forms
What happens in pro-metaphase?
- spindles attach to chromosomes
What happens in metaphase?
- spindles align chromosomes at the midpoint