Inflammatory Bowel Disease Flashcards
What are the two types of IBD?
Crohn’s disease and Ulcerative colitis
Which form of IBD develops at a younger age?
Crohn’s disease
Where do Crohn’s disease and ulcerative colitis typically affect?
Crohns: anywhere from the mouth to the anus, more common in the terminal ileum and colon - is a patchy disease process with skip areas
UC: only the colon and rectum (nearly always involves the rectum) - is continuous
What symptom is typical of IBD?
Bloody diarrhoea
What is the difference in presentation between UC and CD?
CD: abdominal pain, small bowel obstruction, diarrhoea, weight loss, PR blood and anaemia
UC: diarrhoea, blood and mucous (PR)
Which form of IBD has a greater outcome at surgery?
Ulcerative colitis as can completely remove the affected area of bowel
Does IBD follow a linear progression?
No, can go through phases of relapse and remission
What is the gold standard test for diagnosis or IBD?
Colonoscopy and mucosal biopsy
What feature or IBD is specific to Crohn’s disease however is only identified in about 50% of patients?
Granulomas
If fail to respond to medical therapy what is the next line of treatment for IBD?
Surgery
On colectomy, what feature is seen in Crohns disease?
Cobblestoning
Which layers of the bowel wall do Crohns and UC affect?
CD: transmural throughout the entire bowel wall
UC: only the mucosa and submucosa
What is the major, however rare, complication of UC?
Toxic megacolon
What is the main difference is presentation of Crohns and UC?
Abdominal pain present in Crohns disease
What class of drugs should be avoided in IBD?
NSAIDS
