Inflammation_2

Question 1

Basic patterns of inflammation (2)

Answer 1

Acute inflammation

Chronic inflammation

Question 2

> it is earliest reaction of local tissue and their blood vessel to injury
relatively of short duration, lasting from a few minutes to several days - self limiting (start/end)

> characterized by the exudation of fluid and plasma components and emigration of leucocytes (neutrophils) into the extravascular tissue
triggered by stimuli: infection, immune response, trauma, physical or chemical agent and tissue necrosis from any cause

Answer 2

Acute inflammation

*becomes chronic when the healing begins to occur at the same time as active inflammation

Question 3

> the result of a recurrent or progressive acute inflammatory response or form low grade responses that fail to evoke an acute response
of long duration (weeks, months, years)
self perpetuating (more irritation perpetuates irritation)

> Characterized by infiltration of macrophages and lymphocytes instead of the influx of neutrophils and proliferation of fibroblasts rather than exudates formation as seen in acute inflammation

Answer 3

Chronic inflammation

Question 4

2 patterns of chronic inflammation

Answer 4

1) granulomatous formation

2) non specific chronic inflammation

Question 5

> a small lesion which has a mass of macrophages leads to this
associated with foreign bodies (splinters, sutures, silica, asbestos)
foreign bodies are poorly digested and not controlled by other inflammation

Answer 5

Granulomatous formation

• packages stuff up

Question 6

> diffuse accumulation of macrophages and lymphocytes at the site of injury
fibroblast proliferation occurs with subsequent scar formation that replaces the connective tissue

Answer 6

Non specific chronic inflammation

*like crones disease

Question 7

There are 2 types of manifestation of inflammation

Answer 7

1) local

2) systemic

Question 8

this type of manifestation of inflammation can range from swelling and the formation of exudates (goo) to abscess formation and ulceration

Answer 8

Local manifestation

Question 9

exudate fluid type

watery fluids low in protein content, results from plasma entering the inflammatory site

Answer 9

Serous exudates

*blister

Question 10

exudate fluid type

occurs when there is severe tissue injury that causes damage to blood vessels, or when there is significant leakage of red blood cells from capillaries

Answer 10

Hemorrhagic exudates

*bleeding

Question 11

exudate fluid type

develops of mucous membrane surfaces, composed of necrotic cells enmeshed in fibropurulent exudates

Answer 11

Membraneous or pseudomembraneoius exudates

*contained area (tooth abscess,

Question 12

exudate fluid type

contain pus: degraded WBCs, protein, tissue debris

Answer 12

Purulent of suppurative exudates

*found in abscess, pockets of pus-leucocytes, necrotic tissues, bacteria, edema

Question 13

exudate fluid type

large amount of fibrinogen, form a thick and sticky meshwork
characteristic of inflammation in body cavities such as the pericardium and pleura

Answer 13

Fibrinous exudates

*inside body - resolves by scar formation

Question 14

exudate fluid type

Localized area of inflammation containing purulent (puss) exudants

Answer 14

Abscess

*enclosed complication

Question 15

exudate fluid type
a site of inflammation containing where an epithelial surface (skin or gastrointestinal epithelium) has become necrotic or eroded

Answer 15

Ulceration

*open sores

Question 16

this type of manifestation of inflammatory mediators are released into the circulation resulting in prominent systemic manifestations - include

> acute phase response
alteration in white blood cell count
fever
Lymphandenitis (lymph node inflammation)
sepsis (infection in blood) and septic shock

Answer 16

Systemic manifestation