Cellular adaptation, injury and death Flashcards
The cell has the ability to maintain their structure and function when exposed to stressful situations by undergoing adaptive changes, to ensure and maintenance. This is called…
Cellular adaptation
- only when stress is overwhelming (or adaptation ineffectual) that cell injury or death occurs
This type of adaptation occurs in response to appropriate stimulus and ceases when the need for adaptation is removed - Term…
Normal cellular adaptation
Mechanism of cellular adaptation
Process»>
Molecular mechanisms mediatings cellular adaptation
> depend on signals transmitted by Chemical Messengers
» They influence gene function
» these genes fall into 2 categories
1) Housekeeping Genes
2) Differentiating Genes
In many adaptive cellular responses
1) differentiation gene is______
2) housekeeping gene_______
1) altered
2) remains the same (unchanged)
Thus cell is able to change size and form without compromising its normal function
What happens once the stimulus that triggers adaptation is removed?
Cell resumes its previous state of specialized function
Adaptive responses cease once removal of need has occured
Type of gene…
Necessary for normal cell function
Housekeeping Genes
Type of gene…
That determine the differentiating characteristics of a particular cell type.
Differentiating Genes (specific role) triggered by various stress
Term.
Implies that an organ constantly varies and adjusts physiological parameters to maintain stable function
Allostasis
Term.
Implies that an organism remains within a certain range of physiological parameters to maintain stable function
Homeostasis