Inflammation 2- Innate Immunity Flashcards

1
Q

High counts of what in milk are indicative of acute mastitis?

A

Leukocytes

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2
Q

What are the 4 major signs of acute inflammation?

A

Pain, redness, heat, and swelling

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3
Q

What causes pain in acute inflammation?

A

Nerve damage

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4
Q

Vasoactive molecules that leads to increased blood flow causes what 2 signs of acute inflammation?

A

Redness and heat

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5
Q

Vasoactive molecules that lead to increased vascular permeability, and chemotactic molecules that lead to neutrophil emigration, causes which sign of acute inflammation?

A

Swelling

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6
Q

TNF-a, Interleukin 1 and 6, are examples of what?

A

Pro-inflammatory cytokines

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7
Q

What factor do macrophages, monocytes, T-cells, and mast cells produce?

A

Tumor necrosis factor

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8
Q

What type of factors activate cells, had toxic effects, enhances fibroblast growth, collagen synthesis, and bone resorption, and promotes inflammation 1?

A

Tumor necrosis factor

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9
Q

What promotes inflammation, kills cells, affects leukocytes, affects the brain, affects cell growth, affects blood flow, and affects metabolism?

A

Interleukin 1

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10
Q

What regulates the transition from early neutrophil dominated inflammatory process to later macrophage inflammatory process?

A

Interleukin 6

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11
Q

Chronic inflammation= high levels of what?

A

Macrophages

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12
Q

Acute inflammation = high levels of what?

A

Neutrophils

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13
Q

What can have some inhibition of TNF and IL 1?

A

IL 6

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14
Q

What has effect on T and B cells, hepatocytes, and the brain(fever)?

A

IL 6

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15
Q

How many different types of antibodies are there?

A

5

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16
Q

What is the most abundant antibody?

A

IGG

17
Q

What are produced by sentinel cells?

A

Chemokines

18
Q

How many classified families do chemokines have?

A

4

19
Q

What coordinates the migration of cells and dictates the course of many inflammatory and immune responses?

A

Chemokines

20
Q

What is the one additional inflammatory symptom?

A

Loss of function

21
Q

What is an example of vasoactive amines?

A

Mast cells

22
Q

What’s an example of vasoactive peptides?

A

C5a

23
Q

What is an example of vasoactive lipids?

A

Sentinel cells

24
Q

What are the leukocytes doing there?

A

Fighting against microorganisms- phagocytosis

25
Q

How did they get there?

A

Leukocyte extravasation

26
Q

How do leukocytes know where to go?

A

Chemokines