Cells Of Immune System Flashcards
What is the production of immune cells?
Hematopoiesis
What are Immune cells, Red blood cells, Platelets examples of?
Hematopoiesis
What are the 3 major lineages of hematopoiesis?
Erythroid, Myeloid, Lymphoid
What is the most diverse group of hematopoiesis?
Myeloid
What are granulocytes, mast cells, monocytes, and macrophages examples of?
Myeloid
What are examples of lymphoid?
Lymphocytes- T and B cells
What are examples of erythroid cells?
Erythrocytes and platelets
What are the 2 chemical compounds of the hematopoietic growth factors?
Colony-stimulating factors (CSF’s)
Interleukins (IL)
What are antimicrobial effectors, particularly in acute bacterial infections, the primary function of?
Neutrophils
What are neutrophils mechanisms of action?
Phagocytosis, Degranulation
What are anti-parasitic effectors, particularly helminthic infections, Roles in allergies, and
Antiviral action the primary function of?
Eosinophils
What is the mechanism of action of eosinophils?
Degranulation
What is the primary function of basophils?
Mediator of inflammation
What is the mechanism of action of basophils?
Degranulation
What are precursors of macrophages and DC’s the primary function of?
Monocytes
What is the mechanism of action of monocytes?
Limited antimicrobial function in blood
What is the primary function of macrophages?
Immune surveillance
What is detection of threats and release of inflammatory mediators the mechanism of action of?
Macrophages
What is immune surveillance, antigen processing and presentation, the primary function of?
Dendritic cells
What is detection of threats and release of inflammatory mediators the mechanism of action of?
Dendritic cells
What is immune surveillance, mediator and amplifier of inflammation and allergy, the primary function of?
Mast cells
What is detection of threats and release of inflammatory mediators via degranulation or synthesis of lipid medications and cytokines the mechanism of action of?
Mast cells
Where are monocytes, basophils, neutrophils, and eosinophils found?
Blood
Besides blood, where can eosinophils be found?
Tissues lining gastro tract and airways
What is destruction of virally infected cells the primary function of?
NK cells
What is recognition of virally infected cells the mechanism of action of?
NK cells
What is the name of the only cells in the body capable of specifically recognizing and distinguishing different antigens
Lymphocytes
What immune response are lymphocytes responsible for?
Adaptive immune response
What type of antigens are B lymphocytes able to recognize?
Extracellular antigens
What do B lymphocytes produce?
Antibodies
What are B lymphocytes differentiated in?
Plasma cells
In what immune response do B lymphocytes play the main role?
Humoral immune response
What type of antigens do t-lymphocytes recognize?
Intracellular antigens
Do t- lymphocytes produce antibodies?
No
What do t- lymphocytes produce?
Cytokines
In what immune response do t-lymphocytes play the main role?
Cellular immune response
What can t-lymphocytes be differentiated in?
Several types of lymphocytes
Where do b-lymphocytes mature in birds?
Bursa of Fabricius
Where are B lymphocytes matured in mammals?
Bone marrow
Where d t- lymphocytes mature?
Thymus
Where do mature lymphocytes develop?
Bone marrow stem cells
