Infectious diseases of the digestive system Flashcards

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1
Q

What is gastritis?

A

stomach pain/inflammation

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2
Q

What are peptic ulcers?

A

erosions in the gastric/duodenal lining

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3
Q

How were peptic ulcers treated previously? How are they treated now?

A

old school:

  • peptic ulcers caused by excess acid
  • treat with antacids (acid inhibitors 1980s)

In the 1980s, Warren & Marshall discovered Helicobacter pylori (G- curved rod) in specimens from ulcer patients

new school:

  • endoscopy & biopsy
  • urea breath test
  • antibiotics
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4
Q

How does H. pylori cause peptic ulcers?

A

H. pylori neutralizes stomach acid

- bacterial enzyme urease converts urea to CO2 and ammonia (strong base)

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5
Q

How does H. pylori survive in the acidic environment of the stomach?

A

Bacteria break down urea to form ammonia, which neutralizes acid

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6
Q

What is the current cure for peptic ulcers?

A

antibiotics

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7
Q

What is gastroenteritis?

name the microbe(s)

identify type of microbe (e.g., prokaryote, virus, yeast, etc.)

recognize noteworthy symptom(s) for diagnosis

identify mode(s) of transmission

describe prevention and/or treatment

A

name the microbe(s)
- Salmonella sp.

identify type of microbe (e.g., prokaryote, virus, yeast, etc.)
- G- bacillus bacteria

recognize noteworthy symptom(s) for diagnosis
- diarrheal diseases

identify mode(s) of transmission

  • contaminated foods
  • normal flora of animals

describe prevention and/or treatment
- cooked foods

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8
Q

What is salmonellosis? How is it treated?

A

gastroenteritis
- treated w/ hydration

potential invasion followed by septicemia
- treated w/ antibiotics

Prevented by proper cooking and handling of food

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9
Q

For hemorrhagic colitis / enterohemorrhagic diarrhea:

name the microbe(s)

identify type of microbe (e.g., prokaryote, virus, yeast, etc.)

recognize noteworthy symptom(s) for diagnosis

identify mode(s) of transmission

describe prevention and/or treatment

A

name the microbe(s)
- Escherichia coli O157:H7 (EHEC)

identify type of microbe (e.g., prokaryote, virus, yeast, etc.)
- G- bacillus bacteria

recognize noteworthy symptom(s) for diagnosis

identify mode(s) of transmission

  • Vehicle Transmission: undercooked meat and veggies
  • Contact Transmission: livestock

describe prevention and/or treatment
- hydration

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10
Q

For travellers diarrhea:

name the microbe(s)

identify type of microbe (e.g., prokaryote, virus, yeast, etc.)

recognize noteworthy symptom(s) for diagnosis

identify mode(s) of transmission

describe prevention and/or treatment

A

name the microbe(s)
- enterotoxigenic Escherichia coli (ETEC)

identify type of microbe (e.g., prokaryote, virus, yeast, etc.)
- bacteria

recognize noteworthy symptom(s) for diagnosis

  • travelers diarrhea
  • self limiting ganstroenteritis
identify mode(s) of transmission
 - fecal-oral

describe prevention and/or treatment
- hydration

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11
Q

What is intoxication?

A

Food Poisoning

Acute diarrhea with vomiting

  • preformed enterotoxins
  • typically heat-stable
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12
Q

What method should be used to prevent outbreaks of hemorrhagic colitis caused by E. coli O157:H7?

Cook meat thoroughly
Wash hands after touching animals in a petting zoo
Wash produce thoroughly, particularly if it will not be cooked
Monitor cattle for the presence of the bacteria
All of these methods should be used

A

All of these methods should be used

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13
Q

Which of the following describes intoxication food poisoning?

You eat undercooked chicken, Campylobacter multiplies in your intestines and causes diarrhea a day later

A chef with norovirus infection prepares your food and you get infected with this diarrheal illness

You leave your leftovers unrefrigerated for three hours before you reheat them, and then after eating you vomit and have diarrhea an hour later

You eat beef from a cow with bovine spongiform encephalopathy and you develop CJD years later

A

You leave your leftovers unrefrigerated for three hours before you reheat them, and then after eating you vomit and have diarrhea an hour later

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14
Q

For hepatitis A:

name the microbe(s)

identify type of microbe (e.g., prokaryote, virus, yeast, etc.)

recognize noteworthy symptom(s) for diagnosis

identify mode(s) of transmission

describe prevention and/or treatment

A

name the microbe(s)
- Hep A

identify type of microbe (e.g., prokaryote, virus, yeast, etc.)
- virus

recognize noteworthy symptom(s) for diagnosis
- Inflammation of liver and jaundice

identify mode(s) of transmission

  • fecal-oral
  • food contamination

describe prevention and/or treatment
- Inactivated vaccine

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15
Q

For hepatitis B:

name the microbe(s)

identify type of microbe (e.g., prokaryote, virus, yeast, etc.)

recognize noteworthy symptom(s) for diagnosis

identify mode(s) of transmission

describe prevention and/or treatment

A

name the microbe(s)
- Hep B

identify type of microbe (e.g., prokaryote, virus, yeast, etc.)
- virus

recognize noteworthy symptom(s) for diagnosis
- Inflammation of the liver and cirrhosis

identify mode(s) of transmission

  • vehicle transmission: blood and body fluid
  • Oncogenic

describe prevention and/or treatment
- subunit vaccine and passive ab injection

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16
Q

For hepatitis C:

name the microbe(s)

identify type of microbe (e.g., prokaryote, virus, yeast, etc.)

recognize noteworthy symptom(s) for diagnosis

identify mode(s) of transmission

describe prevention and/or treatment

A

name the microbe(s)
- Hep B

identify type of microbe (e.g., prokaryote, virus, yeast, etc.)
- virus

recognize noteworthy symptom(s) for diagnosis

  • chronic infection asymptomatic for many yrs
  • inflammation of liver
identify mode(s) of transmission
 - Blood transmission (needle stick, tattoos)

describe prevention and/or treatment
- New drug available (Harvoni)

17
Q

For which type of hepatitis is a vaccine available?

A
B
C
A and B only
A, B and C
A

A and B only

18
Q

Which type of hepatitis is typically transmitted by contaminated foods?

A

A

19
Q

How did E. coli become so virulent (EHEC)?

A

acquired shiga-toxin gene from bacteriophage