Infectious disease control and outbreak management

Question 1

Infectious disease epidemiology

Answer 1

ID can be spread (human-human or animal-human)
Case may be a risk factor
Individual may be a source without being a case
People may be immune

Question 2

How to calculate R0

Answer 2

Probability of effective contact x number of contacts x duration of infectiousness

Question 3

What is the basic reproduction number?

Answer 3

Average number of secondary cases produced by one primary case in wholly susceptible population
Measure of intrinsic potential for infectious agent to spread

Question 4

What does a large R0 indicate?

Answer 4

Hard to control outbreak

Question 5

Herd immunity threshold

Answer 5

proportion of population that need to be immune for a disease to become stable (R=1 means every case gives rise to one new case)

Question 6

Control definition

Answer 6

Reduction of transmission to pre-defined levels

Question 7

Elimination definition

Answer 7

Reduction of transmission risk to near 0

Question 8

Eradication definition

Answer 8

Reduction of transmission risk to 0