Infectious disease

Question 1

What neurotransmitter is implicated in pathology of Tetanus?

Answer 1

GABA - inhibitory transmitter is blocked causing uncontrolled motor activity

Question 2

Post splenectomy risk of which organisms?

Answer 2

Pneumococcus, meningococcus, haemophilus

Question 3

DOC for animal and human bites

Answer 3

Co-amoxiclav, if penicillin allergy doxy + metro

Question 4

Viral meningitis with low glucose?

Answer 4

Mumps / herpes encphalitis

Question 5

Rx of African trypanosomiasis

Answer 5

IV pentamidine or IV suramin - acute
IV melarsoprol - late stage

Question 6

Rx of American trypanosomiasis

Answer 6

azole or nitroderivatives such as benznidazole or nifurtimox

Question 7

Katayam fever is? and RX?

Answer 7

Acute phase of schistosomiasis. Rx is praziquantel same as schistosomiasis

Question 8

Rx of cryptosporidium in immunocompromised patients

Answer 8

Nitazoxanide / Rifaximin for severe disease

Question 9

Genital warts rx?

Answer 9

topical podophyllum / cryotherapy preferred for solitary lesion

Question 10

Eschar is an indication of what infection?

Answer 10

Rickettsial infection

Question 11

Lassa fever vector

Answer 11

Rodents

Question 12

What test is used for malaria speciation? for parasite burden?

Answer 12

Thin blood film. Thick blood film

Question 13

Mx for recurrent hsv in pregnancy.

Answer 13

Suppressive therapy with acyclovir from 36 weeks, deliver vaginally

Question 14

Mx for primary genital herpes during pregnancy

Answer 14

Elective caesarean section if attack after 28 weeks

Question 15

Key features of disseminated gonococcal infection

Answer 15

tenosynovitis
migratory polyarthritis
dermatitis (lesions can be maculopapular or vesicular)

Question 16

Which medicine causes a rash when given in infectious mononucleosis

Answer 16

Amoxcillin

Question 17

Abx effective against mrsa

Answer 17

vanco, teico, linezolid

Question 18

Which of the following anti-retroviral drugs is most characteristically associated with nephrolithiasis?

Answer 18

Indinavir

Question 19

Limited number of skin lesions, hypoasthesia, hair loss is suggestive of

Answer 19

Tuberculoid leprosy

Question 20

aerosolized pentamidine increases risk of

Answer 20

aerosolized pentamidine is an alternative treatment for Pneumocystis jiroveci pneumonia but is less effective with a risk of pneumothorax

Question 21

mucocutaneous ulceration after travel to central and/or south america

Answer 21

leishmaniasis braziliensis

Question 22

What is the most effective neuroimaging to help differentiate between lymphoma and toxoplasmosis in HIV?

Answer 22

Thallium SPECT