derma Flashcards
mucosal membrane involvement and acantholysis on biopsy?
pemphigus vulgaris caused by antibodies directed against desmoglein 3
Dermatitis herpetiformis biospy shows
IgA deposition in the dermis
Features of pyoderma gangrenosum
pathergy - small bump / lesion turns into large acutely
the edge of the ulcer is often described as purple, violaceous and undermined.
the ulcer itself may be deep and necrotic
neutrophilic dermatosis, neurtophilic infiltration on biopsy
Lichen planus features
purple polygoid papules with white lines running between them
Eczema herpeticum features
in children, associated with asthma and eczema
monomorphic punched-out erosions (circular, depressed, ulcerated lesions) usually 1-3 mm in diameter
admit and iv acyclovir for Mx
Gastric adenoca associated with skin condition?
Acanthosis nigricans
lung ca associated with skin condition?
Erythema gyratum repens is a paraneoplastic eruption with a ‘wood-grain’ pattern and figurate erythema commonly seen in patients with lung cancer
dermatomyositis associated with lung and ovarian ca
drug of choice for urticaria without causing drowsiness
loratadine, 2nd line cetrizine
Psoriasis risk factors
I WANT A LAB
Infliximab
W/drawal of steroids
ACEi
NSAIDs
Trauma
Alc
Lithium
Antimalarials
Beta-blockers
Erythrasma
caused by an overgrowth of the diphtheroid Corynebacterium minutissimum
Wood’s light reveals a coral-red fluorescence.
Topical miconazole or antibacterial are usually effective. Oral erythromycin may be used for more extensive infection
SJS caused by
COP’S PLAN
Carbamazepine
OCP
Phenytoin
Sulphonamides
Penicillin
Lamotrigine
Allopurinol
NSAIDs
Rash due to adverse effects of monoclonal antibodies which are checkpoint inhibitors mx?
Topical corticosteroids
causes of pyoderma gangrenosum
GRIP My LymphS GRIPMLS
Granulomatosis with polyangitis
Rheumatoid arthritis
IBD
Primary biliary cirrhosis
Myleoid leukemia
Myeloproliferative disorders
Monoclonal gammopathy
Lymphoma
SLE
Necrolytic migratory erythema associated with
Glucagonoma
