Infections Flashcards
Endocarditis is an infection of the endocardium, usually in what part?
Valve leaflets
What are common complications associated with endocarditis?
Stroke (15%) and valve surgery (32%)
Who are at high risk of contracting endocarditis?
IVDU
Hemodialysis
DM
HIV
Immunosuppression
Dental Procedures
Valvular Heart Disease
Endovascular Hardware
Where is it more common for vegetation to occur in endocarditis?
Left side of the heart (mitral or aortic valves) due to more turbulent flow, more O2, and valvular disorders more common
What is the number one bacterial cause of endocarditis?
Staph aureus
What are common bugs that cause endocarditis?
Staph aureus
Strep viridans
Enterococci
What are Osler’s Nodes?
Painful raised red lesions on the hands and feet in endocarditis
What are Janeway lesions?
Non-tender, flat, small red lesions on hands or feet in endocarditis
What are splinter hemorrhages?
Capillary hemorrhages under the fingernails (seen in endocarditis)
What are Roth Spots?
Retinal hemorrhages with pale centers (sign of endocarditis)
What is the work-up for endocarditis?
Blood cultures (2-3 sets from 2 different locations)
Echo (TTE with follow-up TEE if positive or high risk)
When should blood cultures be collected in the work-up of endocarditis?
Before empiric antibiotic
What is the Duke criteria for endocarditis?
2 major
1 major + 3 minor
5 minor
What are the major criteria in the Duke Criteria for diagnosing endocarditis?
Positive blood culture
Evidence of endocardial involvement by ECHO
What are the minor criterion in the Duke Criteria for diagnosing endocarditis?
Predisposition
Fever
Microbiogic evidence
Vascular phenomena (Janeway lesions, emboli, etc.)
ECHO findings