Implants Flashcards
methods of hormonal manipulation (7)
castration
age
implants
MGA
genetics
nutrition
health
where is castration an important hormone technique
brazil where implants are not approved for use
how is finished weight determined
body weight where a specific body fat content is reached
steroid hormones
derived from cholesterol
wide variety
estrogenic hormones
estrodiol
non steroidal estrogens
zeranol
androgenic hormones
testosterone
progestin hormones
progesterone
MGA (feed additive)
genomic or direct mechanism of action
effect DNA
regulate transcriptional processed via nuclear translocation
leads to enhanced translation and increased protein synthesis
indirect mechanism of action
binds a target gland resulting in a cascade of events that alter biological activity
IGF-1 indirect effects
IGF1 increase DNa increase protein synthesis increase hypertrophy (cell size)
TBA
trenbolone acetate
direct effect of TBA
increased protein synthesis
indirect effect of TBA
decreased protein catabolism
TBA structural similarity
testosterone and estrogen
what does TBA interphere with
corticotrophin induced stimulation of cortisol production
satillite cells in young and adult calves
high in young calves for hypertrophy
decrease as age require hormones to keep muscle cells
how does estrogen improve growth rate and feed efficiency
by how much
increase N retention
growth rate by 10-20%
FE by 5-8%
net effects of TBA
reduced cortisol
increased protein synthesis
increased IGF 1 levels
comination of estorgens and androgens
additive action
decr cort
incr protein synth
combined has more effieicnt response
been using hormonal implants since the
1950s
first generation implants had effective range
60-200 days
first generation implants FE and ADG
5-10% improve FE
5-15% improve ADG
WW increase in suckling calves with first gen implants
+20-40 lbs