Feed Additives Flashcards
feed additives are
non nutritive substances that you can add to feeds in small quantities to meet goals
goals of feed additives (6)
improve feed efficiency
stimulate production
increase feed acceptance
enhance feed safety
improve animal health
reduce GHG
compendium of medicating ingreidient brochures
specifies species, level of mediation, directions for feeding, and purpose for medicinal ingredients
what groups of animals to antibiotics have the most impact on
young unthrifty or stressed
subtherapudic antibiotic levels were used to
promote growth and improve feed conversion
mode of action of antibiotics in growth (5)
supress mild or unrecognizable infections
reduce growth depressing toxins
reduce microbes destroying nutrients in gut
enhance efficiency of nutrient absorption
channel nutrients away form immune system towards growth
health canada antibiotic use restriction
restricts antibiotic usage in food animals to treatinf specific disease under vet direction
why are in feed antibiotics used
mostly to control liver abscess
liver abscess prevalance in cattle
12-32 % with increase over time
liver abscess impact on ADG and FE
11% reduction in ADG
9.7% reduction in FE
liver scoring system 3 levels
0
A 1 or 2 small abscesses
A+ most severe damage
most common liver abscess bacteria
fusobacterium necrophorum
tylosin dose rate
11ppm
what bacteria does tylosin work against
gram positive mostly
some negative
mechanism of tylosin
inhibits bacteria protein synthesis
tylosin impact over time
trend is decreasing effectivity
how does virginiamycin work
limits rumen lactic acid production minimizing SARA risks
ionophore prescriptions requirement
not needed as doesnt impact human amr
what bacteria do ionophores work on
gram positive
how do ionophores work
improve feed conversion by increasing production of propionic acid
what do ionophores prevent (3)
ketosis, lactic acidosis, bloat
ionophore mechanism of action
attaches to cell membrane of bacteria and protozoa in the rumen
solubilized in lipid bilayer
cation is exchanged for a proton
disrupts ionic gradient resulting in decreased intracellular pH
how do gram negative bacteria resistant ioniphores
outer cell membrane
what results for shift from gram pos to gram neg bacteria
less acetate and butyrate