Immunology - Reticuloendothelial System

Question 1

What contributes to non specific immunity

Answer 1

Question 2

What are monocytes

Answer 2

Blood macrophages
The largest of the lymphoid cells present in peripheral blood

Question 3

What are histiocytes

Answer 3

Tissue macrophages:
Alveolar macrophages - lungs
Kupffer cells - liver

Question 4

List the functions of macrophages

Answer 4

Phagocytosis (directly killing )
Specific immune response (markers)
Secreted biologically active substances

Question 5

What is the primary function of macrophages

Answer 5

Phagocytosis

Question 6

Explain phagocytosis

Answer 6

Macrophages envelops the foreign particle by small pseudopodia
The membranes of pseudopods fuse to form phagosome
Lysosome fuse with the membrane of phagosome to form phagolysosome

Question 7

Most bacteria are killed

Answer 7

Intracellularly

Question 8

Explain the specific immune response function of macrophages

Answer 8

Question 9

Explain the secretion of biologically active substances function of macrophages

Answer 9

Question 10

List the types of macrophages

Answer 10

Neutrophils
Eosinophils
Basophils

Question 11

Explain neutrophils

Answer 11

Question 12

Explain eosinophils

Answer 12

Question 13

Explain basophils

Answer 13

Question 14

Degranulation of mast cells results in what

Answer 14

Anaphylaxis and atopic allergy

Question 15

What are dendritic cells and where are they present

Answer 15

Question 16

Explain histocompatability antigens

Answer 16

Question 17

What are the types of Major Histocompatibility antigens

Answer 17

Class I MHC Antigens
Class II MHC Antigens
Class III MHC Antigens

Question 18

Explain Class I MHC Antigens
(Where present, involved in what, recognized by what)

Answer 18

Question 19

Explain Class II MHC Antigens
(Where found, responsible for what)

Answer 19

Question 20

Explain Class III MHC Antigens

Answer 20

Question 21

What are the indications of HLA typing

Answer 21