Antimicrobial Therapy Flashcards by Лили Ауси | Brainscape

Q

Define Antimicrobial agent

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Q

Explain the term antibiotic

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Q

List the 5 groups of mechanism of action of antibiotics

A

Interfering with cell wall synthesis
Acting on cytoplasmic membrane
Inhibiting protein synthesis
Inhibiting DNA function
Metabolic antagonists

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Q

Explain the interfering with cell wall synthesis mechanism of action of antibiotics

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Q

Explain the acting on cytoplasmic membrane mechanism of action of antibiotics

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Q

Explain the inhibiting protein synthesis mechanism of action of antibiotics

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Q

Explain the metabolic antagonists mechanism of action of antibiotics

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Q

Give example of antibiotics that inhibit protein synthesis

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Q

List the Antimicrobial drugs

A

Penicillin
Cephalosporins
Amino-glycosides
Tetracyclines

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Q

Explain penicillin

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Q

Explain cephalosporins

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Q

Explain amino-glycosides

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Q

Give examples of aminoglycosides

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Q

Explain tetracyclines

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Q

List other antibiotics

A

Macrolides
Clindamycin and linomycin
Vancomycin
Quinolones
Bacitracin
Chloramphenicol
Sulphonamides and trimethoprim

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Q

Explain macrolides

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Q

Lincomycin acts by what

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Q

Explain vancomycin

A

Q

Explain quinolones

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Q

Explain bacitracin

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Q

Explain chloramphenicol

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Q

Explain sulphonamides and trimethoprim

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Q

List the antituberculous drugs

A

Isoniazid
Rifampicin
Cycloserine
Metronidazole

Q

Explain isoniazid

A

Q

Explain rifampin and cycloserine

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Q

Explain metronidazole

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Q

Explain the antibiotic resistance

A

Q

Antimicrobial resistance can be due to what

A

Common mechanisms
Genetic bases

Q

List the common mechanisms of Antimicrobial resistance

A

Permeability
Production of enzymes
Altered structural target
Altered metabolic pathway

Q

Explain permeability mechanism of Antimicrobial resistance

A

Q

Explain production of enzyme mechanism of Antimicrobial resistance

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Q

Explain altered structural target mechanism of Antimicrobial resistance

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Q

Explain altered metabolic pathway mechanism of Antimicrobial resistance

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Q

Explain the genetic basis of resistance and its types

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Q

What are the two types of Antimicrobial sensitivity test

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Q

The disc diffusion tests are used for what

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Q

The disc diffusion uses what

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Q

How is the disc diffusion test performed

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Q

Explain the Kirby - Bauer diffusion method

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Q

Explain the broth dilution methods of Antimicrobial test

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