Antibodies Flashcards

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1
Q

Define antibodies

A
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2
Q

Antibodies are classified as what

A
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3
Q

What is the molecular weight of antibodies

A
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4
Q

Immunoglobulins are primarily synthesized by what

A

Plasma cells

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5
Q

Explain structure of immunoglobulin

A
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6
Q

What are the similarities between both chains

A
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7
Q

How are H chains different

A
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8
Q

Name the class of immunoglobulin and its type of heavy chain

A
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9
Q

Explain light chains and name its two forms

A
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10
Q

What is the effect of enzymes on immunoglobulins

A
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11
Q

What is one Fc (fragment crystallizable) fragment

A
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12
Q

What is the amino acid number in heavy and light chain

A
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13
Q

Both L and H chain consist of what

A
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14
Q

What are immunoglobulin domains

A
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15
Q

What is IgG

A
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16
Q

What is the molecular weight of IgG

A
17
Q

Explain placental transfer of IgG

A
18
Q

Explain functions of IgG

A
19
Q

IgG protects against what

A
20
Q

What is IgA

A
21
Q

What are the forms of IgA

A

Serum and secretory IgA

22
Q

Explain Serum IgA

A
23
Q

Explain secretory IgA

A
24
Q

Secretory IgA exists as what

A
25
Q

What is J chain

A
26
Q

Secretory IgA includes what

A
27
Q

IgA is present in which secretions

A
28
Q

What are the functions of IgA

A
29
Q

What is IgM

A
30
Q

What is the molecular weight of IgM

A
31
Q

How is IgM mainly distributed

A
32
Q

What is the earliest synthesized immunoglobulin by foetus in about 20 weeks of age

A

IgM

33
Q

What is the function of IgM

A
34
Q

What is IgD
(present concentration, distribution, molecular weight)

A
35
Q

Explain where IgE is produced and it’s distribution

A
36
Q

IgE is also referred to as what

A

Reagins

37
Q

What is the molecular weight of IgE

A

190,000 daltons

38
Q

IgE has high affinity to what

A
39
Q

In which diseases is IgE level high

A