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QUIZ 15 > Immunology Intro > Flashcards

Immunology Intro Flashcards

1
Q

small lymphocyte

A

produces B cells or T cells

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2
Q

plasma cell

A

fully differentiated form of B cell that secretes antibodies

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3
Q

natural killer cell

A

kills cells infected with viruses

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4
Q

neutrophil

A

phagocytosis and killing of microorganisms

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5
Q

eosinophil

A

killing of antibody-coated parasites through release of granule contents

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6
Q

basophil

A

controlling immune responses to parasites

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7
Q

dendritic cell

A

activation of T cells and initiation of adaptive immune response

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8
Q

mast cell

A

expulsion of parasites from body through release of granules containing histamine

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9
Q

monocyte

A

circulating macrophage precursor

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10
Q

macrophage

A

phagocytosis and killing of microorganisms; activation of T cells and initiation of immune response

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11
Q

How can you identify a T cell vs B cell?

A

all T cells express CD3; B cells have CD19/CD20; NK cells have CD16/CD56

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12
Q

innate immune system

A

pre-existing, limited specificity, no memory

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13
Q

acquired immune system

A

adaptive, highly specific, has memory

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14
Q

innate immunity includes _

A

epithelial barriers, dendritic cells, NK cells, phagocytes, complement system

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15
Q

adaptive immunity includes _

A

B cells –> antibody and T cells –> effector T cells

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16
Q

innate immunity is initiated within _

A

0-4 hours; infection –> recognition by preformed/non-specific effectors –> removal

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17
Q

early induced innate response occurs within _

A

4-96 hours; infection –> recruitment of effectors –> PAMP recognition for inflammation –> removal

18
Q

adaptive immune response occurs within _

A

more than 96 hours; infection –> transport of antigen to lymphoid organs –> recognition by naive B and T cells –> clonal expansion and differentiation –> removal

19
Q

specificity inherited in the genome

A

innate cells

20
Q

receptors expressed by all cells of a particular type

A

innate cells

21
Q

receptors trigger immediate response

A

innate cells

22
Q

receptors recognize broad class of pathogens

A

innate cells

23
Q

receptors interact with a range of molecular structures

A

innate cells

24
Q

receptors encoded in multiple gene segments

A

adaptive cells

25
Q

receptors require gene rearrangement

A

adaptive cells

26
Q

receptors have clonal distribution

A

adaptive cells

27
Q

receptors are able to discriminate between structures

A

adaptive immunity

28
Q

adaptive immune system cells

A

WBC’s (T cells and B cells) and dendritic cells and macrophages

29
Q

adaptive immune system molecules

A

antibodies, cytokines, chemokines, inflammatory mediators

30
Q

antigen

A

substance that is capable of stimulating an immune response by lymphocytes

31
Q

epitope

A

specific part of an antigen that is recognized by an antibody

32
Q

primary antibody response includes _

A

low levels of IgM first, some IgG later

33
Q

secondary antibody response includes _

A

low levels of IgM and very high levels of IgG

34
Q

CD8 cytotoxic T cells

A

kill virus infected cells

35
Q

CD4 TH1 cells

A

activate infected macrophages and provide help for B cell antibody production

36
Q

CD4 TH2 cells

A

provide help for antibody production; switching to IgE

37
Q

TH2 cells mostly target _

A

helminth and parasites

38
Q

CD4 TH17 cells

A

enhance neutrophil response and promote barrier integrity

39
Q

TH17 cells mostly target _

A

fungi

40
Q

CD4 regulatory T cells

A

suppress T cell response

41
Q

Tfh cells

A

help isotype switching in B cells

QUIZ 15 (16 decks)

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