immunology and micro of the NS

Question 1

Astrocyte

Answer 1

Structural support, repair processes, BBB, regulation of CNS immune responses, metabolic exchanges

Question 2

immune cells of neuroglial

Answer 2

astrocyte and microglia

Question 3

microglia function

Answer 3

macrophage activity

Question 4

oligodendrocyte

Answer 4

myelin production, electric insulation

Question 5

microglia develops from the _______

Answer 5

bone marrow

Question 6

ependymal cells

Answer 6

lining cavities of the CNS

Question 7

are there dendritic cells in CSF?

Answer 7

no

Question 8

astrocytes express _____ and produce ____

Answer 8

TLR4 and produce TGF beta

Question 9

microglial cells are poor ___ but highly _____

Answer 9

antigen presenting cells but highly phagocytic

Question 10

mast cells in perivascular meninges produce ____ and facilitate _____ during inflammation

Answer 10

TNF and facilitate T cell entry during inflammation

Question 11

B cells enter the BBB only during _____

Answer 11

inflammation

Question 12

only ____ T cells can pass the uninflamed BBB

Answer 12

activated

Question 13

most likely causes of bacterial meningitis in newborn infants

Answer 13

• Group B strep
• E coli
• L. monocytogenes