Immunology and metabolic medicine

Question 1

Statin guidance

Answer 1

80mg if known IHD, PVD, CVA

20mg if known 10yr cardio risk >10%

Question 2

When should QRISK2 not be used

Answer 2

T1DM
eGFR < 60
Familial hyperlipidemia

Question 3

Difference between skin prick and patch testing

Answer 3

Skin prick for immediate hypersensitivities

Patch for delayed type reactions

Question 4

Causes of raised ALP and low calcium

Answer 4

Osteomalacia
Renal Failure

Question 5

Vitamin deficiencies

Retinoids
Thiamine (B1)
Niacin (B3)
Pyridoxine (B6)
Biotin (B7)
Folic acid
Cyanocobalmain (B12)
Ascorbic acid (C)
Napthoquinone (K)

Answer 5

Retinoids - night blindness
Thiamine - beriberi (HF, polyneuropathy)
Niacin - dementia, diarrhoea, dermatitis
Pyridoxine - anaemia, seizures, irritibality
Biotin - dermatitis
Folic acid - anaemia, NT defects
Cyanocobalamin - peripheral neuropathy, anaemia
Ascorbic acid - scurvy
Napthoquinone - hemorrhagic disease of the newborn

Question 6

Most common lung cancer in none smokers

Answer 6

Adenocarcinoma