Haem Flashcards

1
Q

Treatment of ITP

A

Steroids

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2
Q

Rouleaux are seen in which condition?

A

Myeloma

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3
Q

Bence jones protein in the urine is a sign of what?

A

MM

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4
Q

Diagnostic criteria for MM

A

one major + one minor or 3 minor if symptomatic

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5
Q

What are the major and minor criteria for diagnosis of MM?

A

Major criteria
Plasmacytoma
30% plasma cells in a bone marrow sample
Elevated levels of M protein in the blood or urine

Minor criteria
10% to 30% plasma cells in a bone marrow sample.
Minor elevations in the level of M protein in the blood or urine.
Osteolytic lesions (as demonstrated on imaging studies).
Low levels of antibodies (not produced by the cancer cells) in the blood.

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6
Q

Heparin reversal agent

A

Protamine

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7
Q

Sickle patients should recieve what every 5 years from what age?

A

pneumococcal polysaccharide vaccine from 2 years

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8
Q

which drug can be used in the long term management of sickle cell disease?

A

hydroxyurea

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9
Q

Which staging system replaced Ann Arbor?

A

Lugano

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10
Q

Tear drop sign on blood film represent which condition?

A

Myelofibrosis
Thallasemia
megaloblastic anaemia

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11
Q

What would the bone marrow tap result in, in myelofibrosis?

A

dry tap - do a trephine biopsy instead

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12
Q

What are the CRAB features in MM

A

Calcium
Renal failure
Anaemia
Bone fractures/lesions

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13
Q

Auer rods indicate which condition?

A

AML

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14
Q

Findings in tumour lysis syndrome?

A

HyperK
High Ph
low Ca

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15
Q

Which drugs are used in the prevention of tumour lysis syndrome?

A

Allopurinol
Rasburicase

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16
Q

Management of cancer patients with VTE

A

6 months DOAC

17
Q

EBV can result in what kind of differential count?

A

Lymphocytosis
Neutropenia

18
Q

In patients with both B12 and folate def, which should be treated first?

A

B12 first

19
Q

Management of CML

A

Imatinib

20
Q

Inheritance pattern of VWD

A

Autosomal dominant apart from type 3 which is AR

21
Q

Drug choice in VWD

A

TXA
Desmopressin

22
Q

Sickle cell is AR

A

true

23
Q

which medication should be given with blood transfusions in beta that major

A

desferroxime (iron chelator)

24
Q

Aplastic crisis in SC disease results in what

A

Acute drop in Hb
Low retics

25
Q

What is the most common cause of thrombophillia

A

Factor V lieden

26
Q

Which is the most common inherited coagulopathy

A

VWD

27
Q

Blood film in DIC shows what

A

Schistocytes