Haem Flashcards
Treatment of ITP
Steroids
Rouleaux are seen in which condition?
Myeloma
Bence jones protein in the urine is a sign of what?
MM
Diagnostic criteria for MM
one major + one minor or 3 minor if symptomatic
What are the major and minor criteria for diagnosis of MM?
Major criteria
Plasmacytoma
30% plasma cells in a bone marrow sample
Elevated levels of M protein in the blood or urine
Minor criteria
10% to 30% plasma cells in a bone marrow sample.
Minor elevations in the level of M protein in the blood or urine.
Osteolytic lesions (as demonstrated on imaging studies).
Low levels of antibodies (not produced by the cancer cells) in the blood.
Heparin reversal agent
Protamine
Sickle patients should recieve what every 5 years from what age?
pneumococcal polysaccharide vaccine from 2 years
which drug can be used in the long term management of sickle cell disease?
hydroxyurea
Which staging system replaced Ann Arbor?
Lugano
Tear drop sign on blood film represent which condition?
Myelofibrosis
Thallasemia
megaloblastic anaemia
What would the bone marrow tap result in, in myelofibrosis?
dry tap - do a trephine biopsy instead
What are the CRAB features in MM
Calcium
Renal failure
Anaemia
Bone fractures/lesions
Auer rods indicate which condition?
AML
Findings in tumour lysis syndrome?
HyperK
High Ph
low Ca
Which drugs are used in the prevention of tumour lysis syndrome?
Allopurinol
Rasburicase
Management of cancer patients with VTE
6 months DOAC
EBV can result in what kind of differential count?
Lymphocytosis
Neutropenia
In patients with both B12 and folate def, which should be treated first?
B12 first
Management of CML
Imatinib
Inheritance pattern of VWD
Autosomal dominant apart from type 3 which is AR
Drug choice in VWD
TXA
Desmopressin
Sickle cell is AR
true
which medication should be given with blood transfusions in beta that major
desferroxime (iron chelator)
Aplastic crisis in SC disease results in what
Acute drop in Hb
Low retics
What is the most common cause of thrombophillia
Factor V lieden
Which is the most common inherited coagulopathy
VWD
Blood film in DIC shows what
Schistocytes
provoked vs unprovoked anticoagulant time
provoked = 3 months
unprovoked = 6 months
