Immunological Memory Flashcards
What’s the primary immune response
The first time that an individual comes into contact with a particular antigen
It’s slower as there aren’t many specific b cells to produce specific antibodies
The patient will develop symptoms as the pathogen increases in number and damages cells
B and T cells produce memory cells which remain in the body for a long time
What’s the secondary immune response
Is when the individual comes into contact with the antigen next time
Clonal selection is much faster , more antibodies are produced in a short amount of time
A rapid response prevents symptoms so the the person is immune
The memory t cells activate and divide into correct type of t cells to kill the pathogen
What’s active immunity
-requires exposure to antigen
-takes a while for protection to develop
- immune system makes its own antibodies
-long term affects as the memory cells are produced
What’s passive immunity
-given antibodies from elsewhere
-doesn’t require exposure to antigen
-immediate protection
-short term as the memory cells aren’t produced
-no memory cells involved
How does a vaccine control diseases
Provides artificial immunity with memory cells
Herd immunity interrupts transmission through people
Ring vaccination - vaccinating all people around victim
It’s difficult for bacteria to spread as most people are immune
what’s the herd affect and what does the vaccination control
in a population virus is destroyed unvaccinated people are likely to come into contact with disease
sometimes parents refuse to get children vaccinated
vaccination controls disease : it provides immunity with memory cells most children are vaccinated when young
herd immunity interrupts transmission through a population
ethical issues
use of testing animals
testing risk to people in medical trials
side affects
expensive
we don’t know who should get priority first
How does vaccination produce antibodies
- Vaccine contains antigens from the pathogen which is weakened which is detected
- The phagocyte displays the antigen on its surface
- T cell with complementary receptor protein binds to antigen
- The T cell then stimulates complementary b cells
5.b cell secreted large amounts of antibodies from the plasma cells - B cell divides when stimulated by T cell chemicals releasing clones and more antibodies