Immunoglobins Flashcards
2 parts of immune response
Humoral immune system
Cellular immune system
Different name for immunoglobulins (Ig)
Antibodies
What produces immunoglobulins?
B Lymphocytes or B cells
What are happens?
Small molecules that can elicit an immune response when covalently attached to large proteins
What do antibodies recognise on the antigen?
The epitopes
What are immunoglobulins divided into classes based on?
Their heavy chain constant regions
How many classes are there of immunoglobulins?
5:
IgA
IgD
IgE
IgG
IgM
What determines which class of immumoglobin?
The constant region
What part of immunoglobins bind onto immune cells?
The bottom part of the constant region
2 places immunoglobins can be found?
Circulating in blood
Attached to immune cells
What is formed when the immunoglobin attaches to the antigen?
Antibody-antigen complex
Which is the main antibody found in our blood? and most abundant in general
IgG
What happens when IgG antibodies bind to viruses?
Neutralisation
Is IgG a monomer or a dimer when secreted by plasma cells?
Monomer
Is IgA a monomere or a dimer when secreted by plasma cells?
Dimer
Which cells secrete antibodies?
Plasma cells
2 forms of IgM antibodies?
Pentamer
Monomer
Antibodies that are secreted as monomers
IgG
IgM
IgE
IgD
Antibodies that are secreted as dimers
IgA
Antibodies that are secreted as pentamers
IgM
