Electron transfer, ATP synthesis and regulation of oxidative phosphorylation Flashcards
What is the structure of complex 1?
L shaped
What is the electron from complex 1 passed to?
Coenzyme q
What does the complex 1 catalyse?
The exergonic transfer of a hydride ion from NADH and a proton from the matrix to ubiquinone
What is complex 2?
Succinate dehydrogenase
What is the electron transferred from and to in complex 3?
From ubiquinone to cytochrome c
Where is the electron transferred from and to in complex 4?
Cytochrome c to O2
What drives the ATP synthesis?
ATP synthase
Which subunits of the ATP synthase are rotating?
Alpha and Beta subunits
What induces the rotation in ATP synthase?
The passage of protons
What changes the conformation of alpha and beta subunits on the ATP synthase?
The rotation of the gamma rod
What happens in the loose conformation of the alpha and beta subunits on the ATP synthase?
ADP and phosphate binds
What happens in the thight conformation of the beta subunits on the ATP synthase?
ADP and phosphate combine to form ATP
What happens in the open conformation of the beta subunits on the ATP synthase?
ATP exits and ADP and phosphate enter
Which subunit of the ATP synthase is the place where ADP and phosphate bind and contact?
Beta
What is the role of the alpha subunit in the ATP synthase?
Regulates the changes in confirmation (stabilises the beta)
