Electron transfer, ATP synthesis and regulation of oxidative phosphorylation

Question 1

What is the structure of complex 1?

Answer 1

L shaped

Question 2

What is the electron from complex 1 passed to?

Answer 2

Coenzyme q

Question 3

What does the complex 1 catalyse?

Answer 3

The exergonic transfer of a hydride ion from NADH and a proton from the matrix to ubiquinone

Question 4

What is complex 2?

Answer 4

Succinate dehydrogenase

Question 5

What is the electron transferred from and to in complex 3?

Answer 5

From ubiquinone to cytochrome c

Question 6

Where is the electron transferred from and to in complex 4?

Answer 6

Cytochrome c to O2

Question 7

What drives the ATP synthesis?

Answer 7

ATP synthase

Question 8

Which subunits of the ATP synthase are rotating?

Answer 8

Alpha and Beta subunits

Question 9

What induces the rotation in ATP synthase?

Answer 9

The passage of protons

Question 10

What changes the conformation of alpha and beta subunits on the ATP synthase?

Answer 10

The rotation of the gamma rod

Question 11

What happens in the loose conformation of the alpha and beta subunits on the ATP synthase?

Answer 11

ADP and phosphate binds

Question 12

What happens in the thight conformation of the beta subunits on the ATP synthase?

Answer 12

ADP and phosphate combine to form ATP

Question 13

What happens in the open conformation of the beta subunits on the ATP synthase?

Answer 13

ATP exits and ADP and phosphate enter

Question 14

Which subunit of the ATP synthase is the place where ADP and phosphate bind and contact?

Answer 14

Beta

Question 15

What is the role of the alpha subunit in the ATP synthase?

Answer 15

Regulates the changes in confirmation (stabilises the beta)

Question 16

Are the beta subunits always in the same or different stages?

Answer 16

Different stages (one is open, one is loose and one is tight)

Question 17

Which stage is the beta subunit in when the gamma protrusion is in it? (ATP synthase)

Answer 17

Always tight

Question 18

Which direction does ATP synthase rotates?

Answer 18

Clockwise

Question 19

Main mechanism of regulation of oxidative phosphorylation

Answer 19

ADP

Question 20

Other mechanism of regulation of oxidative phosphorylation

Answer 20

Oxygen

Question 21

What does the mitochondrial ATP-ADP translocate do?

Answer 21

Transport ADP from cytoplasm into the matrix and ATP from matrix to cytoplasm

Question 22

What is the mitochondrial ATP-ADP translocase?

Answer 22

AN antioporter that transports ATP and ADP

Question 23

Chemical uncoupler of oxidative phosphorylation?

Answer 23

2,4-dinitrophenol (DNP)

Question 24

Is coenzyme Q mobile or non mobile?

Answer 24

Mobile

Question 25

Is coenzyme Q a protein?

Answer 25

No

Question 26

Different name for complex 1

Answer 26

NADH dehydrogensase

Question 27

Different name for complex 2

Answer 27

Succinate dehydrogenase

Question 28

Different name for complex 3

Answer 28

Coenzyme Q cytochrome B oxioreductase

Question 29

Different name for complex 4

Answer 29

Cytochrome oxidase