Immunodeficiency

Question 1

FTT, gastroenteritis, resp tract infections, lymphopenia, opportunistic infection =?

Answer 1

SCID

Question 2

SCID treatment?

Answer 2

stem cell transplant

Somatic gene therapy

Question 3

Recurrent pyogenic bacterial infection=?

Answer 3

B cell immunodeficiency

Question 4

Chronic granulomatous disease is a type of?

Answer 4

Phagocyte deficiency

Question 5

IgA deficiency and common variable immune deficiency are types of what?

Answer 5

B cell immunodeficiency

Question 6

Who will X linked agammaglobulinaemia present in?

Answer 6

Young boys

Question 7

Recurrent prolonged infection that responds poorly to antibiotics. Often staphylococcal, skin and mucous membranes. Supporative lymphadenopathy.

These are symptoms of what?

Answer 7

Phagocyte deficiency

Question 8

What protein is affected in chronic granulomatous disease?

Answer 8

gp91

Question 9

Type of inheritance in chronic granulomatous disease?

Answer 9

X linked recessive

Question 10

Increased susceptibility to bacterial infection =?

Answer 10

C3 deficiency

Question 11

Recurrent neisseria men. infection (meningococcal meningitis)?

Answer 11

C5-8 deficiency

Question 12

Malar rash, arthralgia, fever, glomerular nephritis, vasculitis?

Answer 12

C1,2,4 deficiency

Question 13

How to test complement deficiency?

Answer 13

RBC + RBC antibody = haemolysis