Haematology intro Flashcards

1
Q

What day does haemopoiesis start, expand and disappear?

A

27, 35, 40

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2
Q

What is polycythaemia?

A

Raised RBCs

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3
Q

What is the most common WBC in adult blood?

A

Neutrophils

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4
Q

Neutrophils, eosinophils and basophils are all types of?

A

Granulocytes

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5
Q

Eosinophils are raised in what 3 cases?

A

Parasitic infection
Allergies
Some drugs e.g. aspirin

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6
Q

2 roles of monocytes

A

APC

Phagocytosisi

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7
Q

Monocytes migrate to tissues and are identified as _____or____?

A

Macrophages or histiocytes

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8
Q

Kupffer cells in the liver and langerhans cells in the skin are types of?

A

Monocyte

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9
Q

NK cells innate or adaptive immune system?

A

Innate

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10
Q

Function of NK cells

A

Recognise non-self

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11
Q

Suffix for increased?

A

-cytosis or -philia

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12
Q

Platelets are derived from?

A

Megakaryocytes in BM

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13
Q

5 things tested in FBC

A
Hb conc
MCV
MCHb
WCC
Platelet count
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14
Q

What percentage of normal population falls within the reference range?

A

95%

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15
Q

What do RBCs look like in microcytic anaemia?

A

Pale and small

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16
Q

5 possible causes of microcytic hypochromic anaemia?

A
Fe deficiency
Thalassaemia
Chronic disease
Lead poisoning
Sideroblastic anaemia
17
Q

6 possible causes of normocytic normochromic anaemia

A
Haemolytic
Chronic disease
Acute blood loss
Renal disease
Mixed deficiencies
BM failure
18
Q

2 types macrocytic anaemia

A

Megaloblastic and non megaloblastic

19
Q

Cause of megaloblastic macrocytic anaemia?

A

B12 or folate deficiency

20
Q

Non-megaloblastic macrocytic anaemia causes? (4)

A

Alcohol
Liver disease
Myelodysplasia
Aplastic anaemia