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special stains > immuno markers > Flashcards

immuno markers Flashcards

1
Q

melanoma markers

A

s100
hmb-45
sox10
melanA

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2
Q

s100 is a marker for?

A

melanoma

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3
Q

hmb-45 is a marker for?

A

melanoma

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4
Q

sox10 is a marker for?

A

melanoma

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5
Q

melanA is a marker for?

A

melanoma

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6
Q

CSF tumour markers (glioblastoma etc)

A

GFAP (glial fibrillary acidic protein)

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7
Q

mesothelioma markers?

A

calretinin
WT1

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8
Q

calretinin is a marker for?

A

mesothelioma

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9
Q

lymphoma markers

A

-LCA (leukocyte common antigen) aka CD45

t cells:
– cd3
- cd4
- cd8
- cd7
- cd43

-CD20 (B cells)

-cd30+cd15+ hodgkins lymphoma

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10
Q

CD45 is also known as?

A

LCA (leukocyte common antigen)

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11
Q

LCA (leukocyte common antigen) is also known as?

A

CD45

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12
Q

LCA/CD45 is a marker for?

A

lymphoma

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13
Q

T cell/lymphocyte marker?

A
  • cd3
  • cd4
  • cd8
  • cd7
  • cd43
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14
Q

b cell/lymphocyte marker?

A

cd20

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15
Q

small cell carcinoma markers?

A

chromogranin
synaptophysin
NSE
cd56

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16
Q

AIS (Adenocarcinoma in situ) markers?

A

p16

17
Q

p16 is a marker for?

A

AIS/Adenocarcinoma in situ

18
Q

adenocarcinoma markers?

A

TTF1 (thyroid transcription factor)
Napsin-A
CEA
EMA (epithelial membrane antigen)
CK7 and CK20

19
Q

Squamous cell carcinoma markers?

A

p63
p40
ck5
ck6
ck903
EMA (epithelial membrane antigen)

20
Q

p63 is a marker for?

A

squamous cell ca

21
Q

p40 is a marker for?

A

squamous cell ca

22
Q

which markers confirm Thyroid medullary carcinoma?

A

calcitonin, chromogranin, synpatophysin

23
Q

Specific marker for hodgkin’s lymphoma?

A

CD30+ and CD15+

24
Q

Ovarian cancer marker?

A

CA125

25
Q

CA125 is a marker for?

A

ovarian cancer

26
Q

breast cancer markers

A

her2, neu, brca, ER, PR

27
Q

marker for prostate cancer?

A

PSA Prostate Specific Antigen

special stains (19 decks)

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