Immunity for dummies

Question 1

T helper cells - function

Answer 1

Recognise antigens on MHC II
Cell mediated immune response
Main source IL-2

Question 2

T helper cells - surface receptors

Answer 2

CD 4
CD 28 - co-stimulatory signal

Question 3

Cytotoxic T cells - function

Answer 3

Induce apoptosis
Recognise antigens on MHC I
Cell mediated immune response

Question 4

Cytotoxic T cells - surface receptor

Answer 4

CD 8 - co-stimulatory signal for MHC I

Question 5

B cells - function

Answer 5

Antigen presenting cells via MHC II
Systemic immune response

Question 6

Macrophages - function

Answer 6

Phagocytosis
Source IL-1

Question 7

Macrophages - surface receptors

Answer 7

CD 14

Question 8

NK cells - surface receptors

Answer 8

CD 56

Question 9

Significance CD 4

Answer 9

Used by HIV to enter cells

Question 10

Significant CD 5

Answer 10

Present in most MCL

Question 11

Significance CD 15

Answer 11

Reed-Sternburg cells (Burkitt’s)

Question 12

Significant CD 21

Answer 12

EBV

Question 13

Cells involved acute organ rejection

Answer 13

Helper and cytotoxic T cells

Question 14

Cells involved chronic organ rejection

Answer 14

Helper and cytotoxic T cells

Question 15

Cells involved hyperactive organ rejection

Answer 15

B cells

Question 16

Plasma cells - source

Answer 16

Differentiated from B cells

Question 17

Plasma cells - function

Answer 17

Produce large amounts antibody

Question 18

Neutrophils - function

Answer 18

Main cell in acute inflammation
Phagocytic

Question 19

Basophils - function

Answer 19

Allergic response, IgE mediated