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Physiology MRCP > Hormones > Flashcards

Hormones Flashcards

1
Q

ADH - function

A

Promotes water reabsorption in collecting ducts of kidneys by insertion of aquaporin-2 channels

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2
Q

ADH - source

A

Synthesised hypothalamus
Released by posterior pituitary

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3
Q

ADH - increases secretion

A

Extracellular fluid osmolality increase
Volume decrease
Pressure decrease
Angiotensin II

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4
Q

ADH - decreased secretion

A

Extracellular fluid osmolality decrease
Volume increase
Temperature decrease

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5
Q

PTH - function

A

Increase osteoclast activity
Increase renal tubular reabsorption of calcium
Decrease renal phosphate reabsorption
Increase synthesis of active form of vitamin D –> increase bowel absorption of calcium,

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6
Q

Calcitonin - source

A

C cells of thyroid

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7
Q

Calcitonin - function

A

Inhibit osteoclast activity
Inhibit renal tubular absorption of calcium

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8
Q

Growth hormone - source

A

Somatotroph cells of anterior pituitary

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9
Q

Growth hormone - function

A

Postnatal growth and development
Protein, carbohydrate and fat metabolism - increases lipolysis and gluconeogenesis

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10
Q

Growth hormone - increases secretion

A

Fasting
Exercise
Sleep

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11
Q

Growth hormone - decreases secretion

A

Glucose
Somatostatin (hormone)

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12
Q

Prolactin - source

A

Anterior pituitary

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13
Q

Prolactin - function

A

Breast development
Stimulates milk production

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14
Q

Prolactin - increased secretion

A

Pregnancy
Oestrogen
Breastfeeding
Sleep
Stress
Drugs - metoclopramide, antipsychotics
Thyrotropin releasing hormone

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15
Q

Prolactin - decerases secretion

A

DOPAMINE!! under constant inhibition by dopamine
Dopaminergic agonists

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16
Q

Aldosterone - source

A

Zona glomerulosa of adrenal cortex

17
Q

Aldosterone - function

A

Increase retention of sodium in exchange for K and H

18
Q

Aldosterone - increased secretion

A

Angiotensin II
Potassium
ACTH

Physiology MRCP (19 decks)

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