Immunity and Inflammation Flashcards

Week 5

1
Q

What is a pathogen?

A

Any organism / microbe which can enter the body and cause disease

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2
Q

What is an antigen?

A

A protein (found on pathogens) that stimulates an immune response

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3
Q

What does the innate immune system consist of?

A

Non-specific physical or chemical barriers / defence mechanisms which keep non-self cells from entering the body and causing harm e.g. skin

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4
Q

What does the adaptive immune system consist of?

A

Specific defence mechanism which targets specific antigens on pathogens and develops an immunological memory

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5
Q

Name the mechanisms that act as a first line of defence in the innate immune system

A
  • Skin
  • Sweat
  • Urinary tract - one way flow of urine
  • Mucous membranes
  • Cilia
  • Hair
  • Digestive system - stomach acid
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6
Q

Name the mechanisms that act as the second line of defence of the innate immune system

A
  • Inflammatory response
  • Phagocytosis
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7
Q

What is the scientific name for a white blood cell?

A

Leukocyte

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8
Q

What is a progenitor cell?

A
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9
Q

Major histocompatibility complex…

A
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10
Q

Where do B-lymphocytes / cells mature?

A

In the bone marrow

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11
Q

Where do T-lymphocytes / cells mature?

A

In the thymus gland

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12
Q

B-cells…

A
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13
Q

Humoral response…

A
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14
Q

Plasma cells…

A
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15
Q

Memory B-cells…

A
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16
Q

B-cell receptors…

A
17
Q

T-cells…

A
18
Q

Cell-mediated response…

A
19
Q

Helper T-cells…

A
20
Q

Cytotoxic T-cells…

A
21
Q

Memory T-cells…

A
22
Q

Suppressor T-cells…

A
23
Q

What are the two types of acquired immunity?

A

Active immunity and passive immunity

24
Q

What does the Latin suffix ‘-itis’ suggest?

A

Inflammation / inflammatory response

25
Q

Mast cells…

A
26
Q

Macrophages…

A
27
Q

Chemokines…

A
28
Q

Dendritic cells…

A
29
Q

Pathogen-associated molecular patterns…

A
30
Q

Damage associated molecular patterns…

A
31
Q

Chemotaxis…

A
32
Q

What are the three main non-specific leukocytes present in skin and connective tissue?

A

Mast cells, macrophages and dendritic cells

33
Q

Degranulation and chemical mediator release…

A
34
Q

What is suppuration?

A

Pus

35
Q
A