Immunisation schedule Flashcards
Which two vaccines are given to neonates at birth if they are at risk only?
- Bacillus Clamette-Guerin (BCG) vaccine
2. Hepatitis B vaccine
If a neonate is at risk of hepatitis B, when are the 3 doses of the hepatitis B vaccine given?
- At birth
- 4 weeks
- 1 year
BCG (Bacillus Calmette-Guerin) is a live attenuated strain derived from Mycobacterium (?) which stimulates the development of immunity to Mycobacterium tuberculosis
bovis
The BCG (Bacillus Calmette-Guerin) vaccine against tuberculosis is a (live attenuated/inactivated/toxoid/conjugate) vaccine
Live attenuated
Which patient demographics is the BCG vaccine offered to? (8)
- All infants (0-12 months) with a parent or grandparent who was born in a country with a high incidence of TB*
- All infants (0-12 months) living in areas of the UK with a high incidence of TB
- Previously unvaccinated children aged 1-5 years with a parent or grandparent bone in a country with a high incidence of TB (tuberculin testing not required)
- Previously unvaccinated, tuberculin-negative children aged from 6 to under 16 years of age with a parent or grandparent who was born in a country with a high incidence of TB
- Previously unvaccinated, tuberculin-negative individuals under 16 years of age who are household or equivalent close contacts of cases of sputum smear-positive pulmonary or laryngeal TB
- Previously unvaccinated, tuberculin-negative individuals under 16 years of age who were born in or who have lived for a prolonged period (>/= 3 months) in a country with a high prevalence of TB
- Individuals at occupational risk (healthcare worker, laboratory workers, veterinary and staff) that are exposed to patients or animals with TB
- Those under 16 years who are travelling to stay with friends/family or local people in a country with a high incidence of TB
- high incidence of TB is 40/100,000 or greater per year
** tuberculin test = Mantoux test
BCG can be given up to 3 months following a negative tuberculin test
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/731848/_Greenbook_chapter_32Tuberculosis.pdf
What does a negative Mantoux test look like?
Diameter of induration < 5 mm
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/731848/_Greenbook_chapter_32Tuberculosis.pdf
What does a positive Mantoux test look like?
Diameter of induration >/= 5 mm
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/731848/_Greenbook_chapter_32Tuberculosis.pdf
What factors may suppress the reaction to tuberculin protein in a Mantoux test? (6)
- Glandular fever
- Viral infections (e.g. measles, varicella zoster but NOT upper respiratory tract or gastroenteritis)
- Live viral vaccines received in the previous 4 weeks)
- Sarcoidosis
- Corticosteroid therapy
- Immunosuppression
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/731848/_Greenbook_chapter_32Tuberculosis.pdf
Which neonates should be immunised with a hepatitis B vaccine at birth?
Infants born to hepatitis B infected mothers
To prevent mother to child transmission at or around to the time of birth.
Immunisation of the infant should start as soon as possible after
birth, and no later than 24 hours, and be followed by a dose four and eight weeks later
and a further dose at one year of age.
What 3 vaccine are given to infants at 8 weeks of age?
- Infanrix hexa: diphtheria with tetanus, pertussis, hepatitis B , poliomyelitis and haemophilus influenzae type B vaccine (first dose)
- Bexsero: meningococcal group B vaccine (first dose)
- Rotarix: rotavirus vaccine (first dose)
What 3 vaccines are given to infants at 12 weeks of age?
- Infanrix hexa: diphtheria with tetanus, pertussis, hepatitis B, poliomyelitis and haemophilus influenzae type B vaccine (second dose)
- Prevenar 13: pneumococcal polysaccharide conjugate vaccine (single dose)
- Rotarix: rotavirus vaccine (second dose)
What 2 vaccines are given to infants at 16 weeks of age?
- Infanrix hexa: diphtheria with tetanus, pertussis, hepatitis B, poliomyelitis and haemophilus influenzae type b vaccine (third dose)
- Bexsero: meningococcal group B vaccine (second dose)
What 4 vaccines are given to children on or after their first birthday?
- MMR VaxPRO or Priorix: measles, mumps and rubella vaccine, live (first dose)
- Bexsero: meningococcal group B vaccine (single booster dose)
- Prevenar 13: pneumococcal polysaccharide conjugate vaccine (single booster dose)
- Menitorix: Haemophilus influenzae type b with meningococcal group C vaccine (single booster dose)
Which 2 vaccines are given to children 3 years and 4 months of age (or soon after)?
- Boostrix-IPV or Repevax: diphtheria with tetanus, pertussis and poliomyelitis vaccine (single booster dose)
- MMR VaxPRO or Priorix: measles, mumps and rubella vaccine, live (second dose
Which vaccine is given yearly to children aged 2-15 years (including children in reception class and school years 1-11)?
Influenza vaccine (live attenuated influenza nasal spray is recommended)