Eye Infections Flashcards

1
Q

What is the antibiotic treatment for purulent conjunctivitis?

A

Chloramphenicol eye drops
- Apply 1 drop every 2 hours then reduce frequency as infection is controlled and continue for 48 hours after healing, frequency dependent on the severity of the infection

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2
Q

How long after purulent conjunctivitis has healed should you continue using chloramphenicol eye drops?

A

48 hours

Chloramphenicol eye drops
- Apply 1 drop every 2 hours then reduce frequency as infection is controlled and continue for 48 hours after healing, frequency dependent on the severity of the infection

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3
Q

What are the side effects of using chloramphenicol topically on the eye? (6)

A
  1. Angioedema
  2. Bone marrow disorders
  3. Eye stinging
  4. Fever
  5. Paraesthesia
  6. Skin reactions
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4
Q

Why should you avoid using chloramphenicol (IV, oral, and topical) during pregnancy?

A

Risk of ‘neonatal grey-baby syndrome’

Risk is associated with IV and oral chlorampenicol but topical use should still be avoided unless essential

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5
Q

Why should you avoid using chloramphenicol (IV, oral, and topical) when breastfeeding?

A

Bone-marrow toxicity in infant

Concentration of milk usually insufficient to cause ‘grey syndrome’

Risk is associated with IV and oral chlorampenicol but topical use should still be avoided unless essential

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6
Q

Blepharitis is most commonly caused by which bacteria?

A

Staphylococci

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7
Q

What are the 3 most common causes of bacterial conjunctivitis?

A
  • Steptococcus pneumoniae
  • Staphylococcus aureus
  • Haemophilus influenzae
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8
Q

Which parasite can cause keratitis?

A

Acanthamoeba

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9
Q

If anterior bacterial blepharitis cannot be controlled by eyelid hygiene alone, which antibiotic can be used for treatment?

A

Chloramphenicol eye ointment

- to the conjunctival sac or rubbed into the lid margins

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10
Q

What is the prognosis of most cases of acute bacterial conjunctivitis?

A

Self-limiting

Resolve within 5-7 days without treatment

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11
Q

What should you consider if bacterial conjunctivitis does not resolve with antibacterial eye drops or ointments? (2)

A
  1. Viral conjunctivitis

2. Need for a different antibacterial drug

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12
Q

Can corneal ulcers be treated in primary care?

A

NO

- requires specialist treatment and may call for hospital admission for intensive therapy

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13
Q

Can keratitis be treated in primary care?

A

NO

- requires specialist treatment and may call for hospital admission for intensive therapy

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14
Q

What is involved in the management of endophthalmitis? (3)

A
  • Antibacterial drugs
  • Steroids
  • Surgery (such as vitrectomy) sometimes indicated

MEDICAL EMERGENCY

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15
Q

Which bacteria causes trachoma?

A

Chlamydia trachomatis (chronic infection)

Treated with azithromycin (oral) [unlicensed indication]

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16
Q

Name two eye conditions that are caused by Chlamydia trachomatis?

A
  1. Trachoma

2. Inclusion conjunctivitis

17
Q

What is used for the treatment of trachoma?

A

Azithromycin (oral) [unlicensed indication]

Caused from chronic infection with Chlamydia trachomatis

18
Q

Fungal infections of the cornea (e.g. fungal keratitis) are rare, but which two environmental conditions do they occur in?

A
  1. Agricultural areas

2. Tropical climates