Immune System 31-38 Flashcards

1
Q

Brand-Remicade

A

Generic-infliximab

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2
Q

Brand-Herceptin

A

Generic-trastazumab

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3
Q

Brand-Stelara

A

Generic-ustekinumab

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4
Q

Brand-Xgeva/Prolia

A

Generic-denosumab

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5
Q

Brand-Xolair

A

Generic-omalizumab

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6
Q

Brand-Avastin

A

Generic-bevacizumab

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7
Q

Brand-Gilenya

A

Generic-fingolimod

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8
Q

Brand-SandIMMUNE/Neoral

A

Generic-cyclosporine (NTI)

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9
Q

Class- monoclonal antibodies

A

Remicade,infliximab; Hereceptin,trastazumab; Stelara,ustrkinumab; Xgeva/Prolia,denosumab; Xolair,omalizumab; Avastin,bevacizumab

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10
Q

Stem- (-mab)

A

infliximab; trastazumab; ustrkinumab; denosumab; omalizumab; bevacizumab

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11
Q

Class- immunosuppressant

A

Gilenya,fingolimod; SandIMMUNE/Neoral,cyclosporin

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12
Q

MoA- they bind to the target cells and release toxins

A

Remicade,infliximab; Hereceptin,trastazumab; Stelara,ustrkinumab; Xgeva/Prolia,denosumab; Xolair,omalizumab; Avastin,bevacizumab

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13
Q

QF/Side Effects:
-Can cause fever, chills, weight loss, N/V, hypotension

A

Remicade,infliximab; Herceptin,trastazumab; Stelara,ustrkinumab; Xgeva/Prolia,denosumab; Avastin,bevacizumab

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14
Q

QF/Side Effects:
-Avoid milk as it decreases absorption of med
-Avoid grapefruit juice

A

Gilenya,fingolimod; SandIMMUNE/Neoral,cyclosporin

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15
Q

Uses- Chron’s and Psoriasis

A

Remicade,infliximab

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16
Q

Uses- Cancer

A

Herceptin,trastazumab

17
Q

Uses- Psoriasis

A

Stelara,ustrkinumab

18
Q

Uses- Osteoporosis

A

Xgeva/Prolia,denosumab

19
Q

Uses- Cancer

A

Avastin,bevacizumab

20
Q

Uses- Asthma

A

Xolair,omalizumab

21
Q

Uses- MS

A

Gilenya,fingolimod

22
Q

Uses- Organ Transplant

A

SandIMMUNE/Neoral,cyclosporin (NTI)