Immune System 31-38 Flashcards
Brand-Remicade
Generic-infliximab
Brand-Herceptin
Generic-trastazumab
Brand-Stelara
Generic-ustekinumab
Brand-Xgeva/Prolia
Generic-denosumab
Brand-Xolair
Generic-omalizumab
Brand-Avastin
Generic-bevacizumab
Brand-Gilenya
Generic-fingolimod
Brand-SandIMMUNE/Neoral
Generic-cyclosporine (NTI)
Class- monoclonal antibodies
Remicade,infliximab; Hereceptin,trastazumab; Stelara,ustrkinumab; Xgeva/Prolia,denosumab; Xolair,omalizumab; Avastin,bevacizumab
Stem- (-mab)
infliximab; trastazumab; ustrkinumab; denosumab; omalizumab; bevacizumab
Class- immunosuppressant
Gilenya,fingolimod; SandIMMUNE/Neoral,cyclosporin
MoA- they bind to the target cells and release toxins
Remicade,infliximab; Hereceptin,trastazumab; Stelara,ustrkinumab; Xgeva/Prolia,denosumab; Xolair,omalizumab; Avastin,bevacizumab
QF/Side Effects:
-Can cause fever, chills, weight loss, N/V, hypotension
Remicade,infliximab; Herceptin,trastazumab; Stelara,ustrkinumab; Xgeva/Prolia,denosumab; Avastin,bevacizumab
QF/Side Effects:
-Avoid milk as it decreases absorption of med
-Avoid grapefruit juice
Gilenya,fingolimod; SandIMMUNE/Neoral,cyclosporin
Uses- Chron’s and Psoriasis
Remicade,infliximab