Endocrine 1-8 Flashcards
Brand- Glucotrol
Generic- glipizide
Brand- Amaryl
Generic- glimepiride
Brand- Diabeta
Generic- glyburide
Brand- Glucophage
Generic- metformin
Brand- Actos
Generic- pioglitazone
Brand- Januvia
Generic- stiagliptin
Brand- Invokana
Generic- canglinflozin
Brand- Victoza
Generic- liraglutide
Stem- (-ide)
glipizide; glimepiride; glyburide
Class- 2nd generation sulfonylureas
Glucotorol,glipizide; Amaryl,glimepiride; Diabeta,glyburide
MoA- promote insulin release from the pancreatic beta cells
Glucotorol,glipizide; Amaryl,glimepiride; Diabeta;glyburide
Uses- Type II Diabetes
Glucotorol,glipizide; Amaryl,glimepiride; Diabeta;glyburide; Actos,pioglitazone; Januvia,stiagliptin; Invokana,cangliflozin; Victoza,liraglutide
Stem- (-formin)
Glucophage,metformin
Class- Biguanide
Glucophage,metformin
MoA- reduce hepatic glucose production, increase intestinal glucose absorption, and increases insulin sensitivity
Glucophage,metformin
Uses- Type II Diabetes, POCS, (polycystic ovary disease)
QF/Side Effects:
-Can cause diarrhea, N/V, flatulence, metallic taste in mouth
-TAKE WITH MEALS
Glucophage,metformin
Class- Thiazolidinediones (TZD)
Actos,pioglitazone
MoA- promotes better use of glucose by the cells
Actos,pioglitazone
QF/Side Effects:
-Can cause upper respiratory infections, H/A, fluid retention, edema, weight gain
Actos,pioglitazone
QF/Side Effects:
-Can cause hypoglycemia, dizziness, H/A, nausea, photosensitivity
Glucotorol,glipizide; Amaryl,glimepiride; Diabeta;glyburide
QF/Side Effects:
-Can cause upper respiratory infections, H/A, abdominal pain
Januvia,stiagliptin
QF/Side Effects:
-Can cause infection in the penis or vulvoaginal area, hypoglycemia, UTI, increased urination
Invokana,cangliflozin
QF/Side Effects:
-Can cause N/V, diarrhea, constipation, dyspepsia, and vomiting
-Given by injection
Victoza,liraglutide
