Cardiac 21-30 Flashcards
Brand-Coumadin
Generic-warfarin
Brand-Heparin
Generic-heparin sodium
Brand-Fragmin
Generic-dalteparin
Brand-Lovenox
Generic-enoxaparin
Brand-Paradax
Generic-dabigatran
Brand-Eliquis
Generic-apixaban
Brand-Xarelto
Generic-rivaroxaban
Brand-Plavix
Generic-clopiogrel
Brand-Epogen
Generic-epoeitin alfa
Brand-Feosol
Generic-ferrous sulfate
MoA-inhibits the actions of Vitamin K clotting factors
Coumadin/warfarin
Class- anticoagulant
Coumadin/warfarin, Heparin/heparin sodium
QF/Side Effects:
-AVOID food rich in Vitamin K and citrus
-Can increase risk of bleeding
-(NTI) needs lab levels drawn - PT (prothrombin time) & INR (internationalized normal ratio)
-Broad spectrum antibiotics can increase bleeding risk
-Taken with SSRIs can increase bleeding risk
-Avoid taking with alcohol
-Antidote is Vitamin K (mephyton) or Kcentra (a prothrombin complex concentrate)
Coumadin/warfarin
MoA- prevents thrombin formation of fibrin to form clots
Heparin/heparin sodium
Uses- clot prevention and thinning of blood
Coumadin/warfarin, Heparin/heparin sodium
QF/Side Effects:
-(NTI) needs lab levels drawn - PTT (partial thromboplastin time0 & INR (internationalized normal ratio)
-only given IV or SQ
-avoid taking with alcohol
-antidote is protamine sulfate
Heparin/heparin sodium
Class- Low molecular weight heparin
Fragmin/dalteparin, Lovenox/enoxaparin
MoA- inhibits clotting factors
Fragmin/dalteparin, Lovenox/enoxaparin
Uses-Prevention of DVT
QF/Side Effects:
-Avid foods rich in Vitamin K and alcohol
-Taken with SSRIs can increase risk of bleeding
Fragmin/dalteparin, Lovenox/enoxaparin
Class- Direct Thrombin Inhibitor
Pradaxa/dabigatran
MoA- blocks thrombin to prevent clots
Pradaxa/dabigatran
QF/Side Effects:
-Antidote is Praxbind
-moisture sensitive
-must be stored in its original container and is only good for four months after opening
Pradaxa/dabigatran
Class- Factor Xa inhibitor
Eliquis/apizaban, Xarelto/revaroxaban
MoA- Blocks Factor Xa preventing clot formation
Eliquis/apizaban, Xarelto/revaroxaban