GI 1-10 Flashcards
Brand- Tagamet
Generic- cimetidine
Brand- Pepcid
Generic- famotidine
Brand- Nexium
Generic- esomeprazole
Brand- Prevacid
Generic- lansoprazole
Brand- Prilosec
Generic- omeprazole
Brand- Protonix
Generic- pantoprazole
Brand- Aciphex
Generic- rabeprazole
Brand- Sancuso
Generic- granisestron
Brand- Zofran
Generic- ondansetron
Brand- Reglan
Generic- metoclopramide
Stem- (-tidine)
cimetidine; famotidine
Class- H2 Blocker (Histamine Antagonists)
Tagamet,cimetidine; Pepcid,famotidine
MoA- decrease acid production by preventing the binding of histamine at the H2 receptors on gastric cells
Tagamet,cimetidine; Pepcid,famotidine
Uses- GERD & Ulcers
QF/Side Effects:
-Can cause H/A, dizziness, nausea, confusion, agitation
Tagamet,cimetidine; Pepcid,famotidine
Stem- (-prazole)
esomeprazole; lansoprazole; omeprazole; pantoprazole; rabeprazole
Class- Proton Pump Inhibitor (PPI)/Anticulcer Agend
Nexium,esomeprazole; Precacid,lansoprazole; Prilosec,omeprazole; Protonix,pantoprazole; Aciphex,rabeprazole
MoA- suppresses acid secretion at the secretory surface of gastric cells
Nexium,esomeprazole; Precacid,lansoprazole; Prilosec,omeprazole; Protonix,pantoprazole; Aciphex,rabeprazole
Uses- GERD, treatment of ulcers, and treatment of H.Pylori
QF/Side Effects:
-Can cause H/A, nausea, diarrhea, and abdominal pain
-Prilosec can reduce the effects of Plavix
Nexium,esomeprazole; Precacid,lansoprazole; Prilosec,omeprazole; Protonix,pantoprazole; Aciphex,rabeprazole
Stem- (-setron)
granisestron; ondansetron
Class- 5-HT3 Receptor Antagonist
Sancuso,granisestron; Zofran,ondansetron
MoA- Blocks serotonin 5-HT3 receptors in the GI tract
Sancuso,granisestron; Zofran,ondansetron
Uses- Nausea and vomiting
QF/Side Effects:
-can cause H/A, constipation, fatigue, and diarrhea
Sancuso,granisestron; Zofran,ondansetron
Class- Dopamine Antagonist
Reglan,metoclopramide
MoA- blocks dopamine receptors producing an antiemetic effect
Reglan,metoclopramide
Uses- nausea and vomiting and gut motility stimulator
QF/Side Effects:
-can cause drowsiness, fatigue, and restlessness
Reglan,metoclopramide