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Pathophysiology > Immune System > Flashcards

Immune System Flashcards

1
Q

what lines make up innate immunity

A

first and second line

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2
Q

effects of histamine

A

vascular dilation and increased capillary permeability

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3
Q

cell-mediated responders for adaptive immunity

A

cytotoxic T cells (CD8+), CD4+ (helper T’s/Th1), natural killer cells

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4
Q

humoral responders for adaptive immunity

A

CD4+ (helper T’s/Th2), B cells

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5
Q

APCs

A

dendritic cells, macrophages, and B lymphocytes

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6
Q

antibody responsible for long term immunity, can cross placenta, and most abundant

A

IgG

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7
Q

antibody primarily found in GI, respiratory and GU tracts

A

IgA

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8
Q

antibody that immediately responds to acute exposures

A

IgM

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9
Q

antibody responsible for allergic response and parasitic infections

A

IgE

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10
Q

clinical stages of infectious disease

A

incubation, prodromal, invasion, convalescence

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11
Q

3 kinds of convalescence

A

recovery, death, latency

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12
Q

capacity to cause disease depends on

A

communicability, immunogenicity (can it get immune response?), infectivity (ability to get in & multiply), mechanism of action, entry portal, pathogenicity, virulence, toxigencity

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13
Q

disease type: TB

A

bacteria

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14
Q

disease type: pneumonia

A

bacteria

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15
Q

disease type: strep

A

bacteria

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16
Q

disease type: pertussis

A

bacteria

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17
Q

disease type: bubonic plague

A

bacteria

18
Q

disease type: cnadidiasis

A

fungi

19
Q

disease type: tinea pedis

A

fungi

20
Q

disease type: ringworm

A

fungi

21
Q

disease type: histoplamosis

A

fungi

22
Q

disease type: aspergillus

A

fungi

23
Q

disease type: HIV

A

virus

24
Q

disease type: influenza

A

virus

25
Q

disease type: herpes

A

virus

26
Q

disease type: hepatitis

A

virus

27
Q

disease type: common cold

A

virus

28
Q

disease type: measles

A

virus

29
Q

disease type: mumps

A

virus

30
Q

disease type: COVID-19

A

virus

31
Q

disease type: worms and bugs

A

helminthes/parasites

32
Q

disease type: amebic meningoencephalitis

A

protozoa

33
Q

disease type: malaria

A

protozoa

34
Q

disease type: trichomoniasis

A

protozoa

35
Q

disease type: toxoplasmosis

A

protozoa

36
Q

disease type: giardiasis

A

protozoa

37
Q

ways bacteria avoids immune system

A

rapid multiplication, protective and mimicking coating, inhibiting lysosome binding, inactivate digestion, and invading phagocytes to trigger explosion of cell

38
Q

Endotoxic shock

A

septic shock caused by endotoxins released from LPS in gram-negative bacteria resulting in multi-organ failure and death

39
Q

primary immune deficiency

A

genetically-linked, present early in life, mold ones unusual, severe ones very rare

40
Q

secondary immune deficiencies

A

more common and acquired from disease and nutritional deficiencies

Pathophysiology (11 decks)

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