Immune Defenses & Lymphoid Tissues Flashcards
The body’s specific protective response to foreign agent/organism
Immunity
Immune system consist of
Bone marrow and lymph tissue
WBCs are formed in?
Bone Marrow, generated from stem cells
Examples of Lymphoid Tissues
Adenoids
Tonsils
Lymph Nodes
Thymus Gland
Spleen
Some tissuesIn GI Tract, Respiratory & Reproductive Systems
Lymphoid Tissues contain high amounts of WBCs. T or F
True
develops throughout life as body is exposed to certain microbes/pathogens/vaccines; immune response is specific to the pathogen exposed to it
Acquired Immune system
immune system/ response that sometimes makes errors and attacks self cells; involves B Cells and T cells
Acquired Immune System
type of immunity where defenses are developed by person’s own body (by vax or contracting diseases); can last lifetime
Active acquired immunity
type of immunity that is temporary & transmitted from another source ; ex; (mother/IV antibodies)
Passive acquired
Damaging reaction of the immune system against “self” antigens; immune system attacking itself
Auto immune diseases
Examples of Natural Immunity Line of Defenses
Skin
Mucous Membranes
Normal Microbiota
Phagocytes
Inflammation
Fever
Leukocytes (WBCs) divided into 2 categories
Granulocytes- Neutrophils, Basophils, Eosinophils
Agranulocytes-Monocyte, Lymphocyte
lymphocyte cells that make antibodies; turns into plasma cells & produces antibodies; involved in adaptive immunity
B cells
lymphocyte cells that mature in thymus; involved in adaptive immunity
T cells
Proteins that function as chemical messengers, allows cells to communicate
cytokines
cells that engulf and digest microbes
phagogcytes
nonspecific response; immune defense system you’re born with; involves barriers that are to keep pathogens from entering the body
Natural/Innate Immune System
Examples of physical/chemical barriers of natural immunity
Cilia
Hydrochloric Acid
Enzyme in Tears/ Saliva
lymphoid organ that stores and filters blood; storage are for lymphocytes & macrophages
spleen
Antibodies aka
Immunoglobins
cells that get rid of antigens & are responsible for humoral immune response
B Lympchocytes/ B cells
cells that recognize foreign material. cells must mature before they respond; produce cellular immune response
T lymphocytes/ T cells
T cells do not require maturation for response. T or F
FALSE!!!
T cells do REQUIRE maturation before response
T cells mature where?
in Thymus
B cells mature where?
B cells stay in Bone Marrow for maturation
areas through out the body that remove foreign materials from the lymph before it enters bloodstream
Lymph nodes
Must numerous WBC
Neutrophils
What does inflammation do?
Limits injury
part of Natural Immunity
Syx of Localized infection
Erythema/ Redness
Warmth
Swelling/Edema
Pain/Tenderness
Pus
Syx of Systemic Infection
Fever/Chills
Cold, Clammy Skin
Elevated WBC count
Decreased Urine Output
Tachycardia/Tachypnea
Change in LOC
Low BP
Englarged Lymph Nodes
Fatigue
Loss of Appetite
Examples of Infectious Agents
Bacteria
Viruses
Fungi
Parasites
3 types of Immune Responses
Phagocytic Response- WBCs that ingest. engulf. destroy
Humoral Response- B cells/ antibody response
Cellular Response- T cells that attack pathogens
Stages in Immune Response
Recognition Stage
Proliferation stage
Response Stage
Effector Stage
stage where WBCs coat organism w/ antibodies/ recognizes antigen as foreign
Recognition stage
stage where antigen message is received and dormant B cells and T cells prepare for destruction
Proliferation Stage
stage where lymphocytes function in either a humoral or cellular fashion
Response Stage
stage where antigens are destroyed by antibodies or killer T cells
Effector Stage
