IM1-Exam 7 Flashcards
Sleep is _____ process
Physiological
What is sleep associated with
Recumbency and & Immobility
What is Recumbency?
“to be laying down”
When sleeping you __1__ conscious awareness but are __2__ awakened?
1.Lack
2. Easily
True or false: Sleep is not essential for healthy functioning and survival?
False- It is essential for healthy functioning and survival
What is sleep?
Sleep is the state in which an individual lacks conscious awareness of environmental surroundings but can be easily aroused
What is insufficent sleep?
Obtaining the less than recommended amount of sleep. (most adults require 7-8 hours in a 24 hour period)
What is the recommended amount of sleep for an adult?
Most adults require 7-8 hours in a 24 hour period
What is fragmented sleep?
Frequent arousal or actual awakenings that interrupt sleep
What is nonrestorative sleep?
Sleep that is of adequate duration but does not result in the individual feeling refreshed and alert the next day
Sleep disturbances are the result of ______?
Conditions of poor sleep quality
Sleep disorders are the result of _____?
Abnormalities unique to sleep.
What are some examples of sleep disorders?
- Insomnia
- Narcolepsy
True or false: Daytime sleepiness can interfere with daily living?
True
What controls a person’s sleep-wake cycle? (general anwser)
The brain.
More specifically what part of a persons brain plays a role in a person’s sleep wake cycle?
- The RAS (Reticular Activating system)
- Orexin (Hypocretin)- Neuropeptide that comes out of the hypothalamus.
What is orexin (hypocretin)?
Neuropeptide that comes out of the hypothalamus that helps regulate sleep/wake cycle.
What are some things we should know about the RAS (Reticular activating system).
- Sensory stimuli within cerebral cortex
- Regulates sleep-wake cycle
- 4 functions
-Motor- Sensory
- Visceral
- Consciousness
What part of our body manages our Circadian Rhythm?
- Suprachiasmatic nucleus (SCN) in hypothalamus
Our Circadian Rhythm is synchronized through ______ in retina
Light detectors
What is the strongest cue for our circadian rhthym.
Light
What are somethings we should know about our circadian rhythm?
- Managed by the suprachiasmatic nucleus (SCN) in hypothalamus
- Synchronized through light detectors in retina
- Light is the strongest time que
True or false: Patients in ICU can suffer from ICU psychosis
True
How many phases of sleep are there
3
What does NREM stand for?
Non rapid eye movement
What phase is the majority of our sleep spent in?
NREM
What are the phases of sleep?
- Sleep Latency
- NREM (3 stages)
- REM (rapid eye movemet
What is sleep latency?
This is the time it takes for a person to fall asleep.
When does sleep latency start?
- Starts when eyes are closed for sleep
When does sleep latency end?
Ends when non-rem sleep is entered
True or false: The time spent in “sleep latency” is usually 10-40 minutes sometimes longer?
True
What percentage of sleep is spent in the NREM stage?
75%-80% of sleep time
What are the stages of NREM?
Stage 1: Slow eye movement
Stage 2: HR and temperature decrease
Stage 3: Deep or slow wave sleep (SWS) delta, waves, parasomnias
True or false: The older we get the more deep sleep we get?
False- The older we get the less deep sleep we get.
What is happening in stage 1 in NREM sleep?
- Slow eye movements
What is happening in stage 2 NREM sleep?
HR and temp decrease
What is happening in stage 3 NREM sleep?
Deep or slow wave sleep (SWS); delta waves, parasomnias
What is parasomnias?
Unusual and often undesirable behaviors while falling asleep, transitioning between sleep stages, or during arousal from sleep
What causes parasomnias?
CNS activation
What are some actions that can happen as a result of parasomnias?
- sleepwalking
- Sleep terrors
- Nightmares
- Sleep paralysis
- sleep hallucinations
What percentage of sleep is spent in the REM stage?
20 to 25%
How often does REM sleep occur?
3 to 4 times a night
In what stage of sleep is skeletal muscle tone greatly reduced?
REM sleep
In what stage of sleep do we experience most of our vivid dreams?
REM
During what stage of sleep is the brain very active but mentally restful?
REM sleep
Middle-aged people experience what changes to their sleep?
- More stage shifts- decreased NREM3 and REM
- Resistant to sleep deprivation
- Increased awaking’s
- Changes in sleep efficiency
Older adults experience what changes to their sleep?
- Phase changes- go to bed earlier and arise earlier
What effects can sleep deprivation have on the neuro system
- Cognitive impairment
- Behavioral changes (e.g., irritability, moodiness)
What effects can sleep deprivation have on your immune system?
- Impaired function
What effects can sleep deprivation have on your respiratory system?
- Asthma exacerbated during sleep
What effects can sleep deprivation have on your cardiovascular system?
- Heart disease (hypertension, dysrhythmias)
- Increased BP in people with hypertension
- Stroke
What effects can sleep deprivation have on your gastrointestinal system?
- Risk for obesity
- Gastroesophageal reflux disease (GERD)
What effects can sleep deprivation have on your endocrine system?
- Increased risk for type 2 diabetes
- Increased insulin resistance
- Decreased growth hormone
Hospitalization are associated with decreased sleep time due to what factors?
- Enviromental sleep-disruptive factors (light & noises)
- Psychoactive medications (drugs)
- Acute and critical illness
What are symptoms of insomnia?
- Difficulty falling asleep
- Difficulty staying asleep
- Waking up too early
- Complaints of waking up feeling unrefreshed.
What is acute insomnia?
Difficulty falling asleep or remaining asleep for at least 3 nights/week for less than a month
What is chronic insomnia?
- Difficulty falling asleep or remaining asleep for at least 3 nights/week for less than a month
- Daytime symptoms that persist for 1 month or longer
Insomnia is aggravated by what?
inadequate sleep hygiene
What are some inadequate sleep hygiene factors?
- Stimulants
- Medications
- Using alcohol to induce sleep
- Irregular sleep schedules
- Nightmare
- Exercising near bedtime
- Jet lag
True or false: Alcohol reduces REM sleep?
True– causes interrupted sleep?
Why should you not exercise near bedtime?
Should not exercise two hours prior to bedtime because it will raise your metabolism and make it harder for you to fall asleep.
True or false: The cause of chronic insomnia is often unknown?
True
What could be some likely causes of chronic insomnia?
- Stressful life event
- Psychiatric illness or medical condition
- Medications or substance abuse
What are the clinical manifestations of insomnia?
- Difficulty falling asleep (long sleep latency)
- Frequent awakening (fragmented sleep)
- Prolonged nighttime awakenings
- Feeling unrefreshed on awakening (nonrestorative sleep)
- Fatigue, trouble with concentration
- Forgetfulness, confusion
- Anxiety
How is insomnia typically diagnosed?
- Self report
- Actigraphy
- Polysomnography (PSG)
What is the 1st thing we will ask a patient do when they think they have insomnia?
Keep a sleep journal for two weeks of when they went to bed, what time they woke up, if they woke up during the night, if they woke up feeling refreshed.
What is an actigraphy?
Watch like device, worn on the wrist, that can determine sleep and wake over a 14 day period.
What is a polysommongraphy?
Sleep study– records breathing patterns, thoracic movements, pulse ox, heart rate, sleep waves
What are things we can do for our patients with insomnia?
- Education
- Track sleep
- Sleep hygiene
- Cognitive-behavioral therapy for insomnia (CBT-I)
- Complementary and alternative therapies
- Drug therapy
What are some sleep hygiene techniques we can teach our patients?
- Do not go to bed unless you are sleepy
- If you are not asleep after 20 minutes, get out of bed and do non-stimulating activities. Return to bed only when you are sleepy.
- Adopt a regular pattern in terms of bedtime and awakening.
- Begin rituals that help you relax each night before bed.
Refer to slide 32 for more examples
What are some causes on insomnia?
- Psychiatric
- Medical illness, medications
- Stress: finances, employment, school, life
- Substances: Caffeine, alcohol, nicotine
- Exercise
- Age, gender
- Other factors: travel
True or false: Tx for insomnia should begin with the most invasive method?
False
Cognitive behavior therapy and counseling can be treatments for insomnia?
Yes
What are some drugs used to treat insomnia?
- Benzodiazepines
- Benzodiazepine-receptor-like agents
- Melatonin-receptor agonists
- Antidepressants
- Antihistamines
- Alternative therapies
What should we know about sedative-hypnotic drugs
1.Depress the CNS function
2. primarily used to tx anxiety and insomnia
3. Antianxiety agents or anxiolytics
4. distinction between antianxiety effects and hypnotic effects depends on dosage
What are some things we should know about benzodiazepines?
- used to tx anxiety and insomnia
- Used to induce general anesthesia
- Used to manage seizure disorders, muscle spasms, panic disorder, and alcohol withdrawal
- potential for abuse
- Can produce physical dependence
What benzodiazepines are used specifically for sleep?
- Temazepam (Restoril)
- Triazolam (halcion)
What are two common types of benzodiazepines not usually used in sleep? DOUBLE CHECK I THINK THIS IS WRONG
- Diazepam (valium)
- Lorazepam (Ativan)
- Alprazolam (Xanax)
What are the pharmacologic effects of benzodiazpines?
- CNS: reduce anxiety and promote sleep
- Cardiovascular system: oral vs. intravenous
- Respiratory system: weak respiratory depressants
What are the therapeutic uses of benzodiazepine?
- Anxiety
- Insomnia
- Seizure disorders, muscle spasm
- ETOH withdrawal, perioperative application